The inhibitory receptor FcγRII reduces joint inflammation in immune complex arthritis not only by inhibition of activatory FcγR but also by efficient clearance of immune complexes

被引：0

作者：

PL van Lent

K Nabbe

AB Blom

AE Holthuysen

S Verbeek

WB van den Berg

机构：

[1] University Medical Center,Department of Experimental Rheumatology and Advanced Therapeutics

[2] University Medical Center,Department of Human Genetics

来源：

Arthritis Res Ther | / 5卷 / Suppl 1期

关键词：

Knee Joint; Immune Complex; Inhibitory Receptor; Joint Inflammation; Cartilage Destruction;

D O I：

10.1186/ar742

中图分类号：

学科分类号：

摘要：

引用

共 18 条

[11] R406, an orally available spleen tyrosine kinase inhibitor blocks Fc receptor signaling and reduces immune complex-mediated inflammation
Braselmann, Sylvia
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Baluom, Muhammad
Qu, Kunbin
Herlaar, Ellen
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Young, Chi
Wong, Brian R.
Lovell, Scott
Sun, Thomas
Park, Gary
Argade, Ankush
Jurcevic, Stipo
Pine, Polly
Singh, Rajinder
Grossbard, Elliott B.
Payan, Donald G.
Masuda, Esteban S.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2006, 319 (03): : 998 - 1008
[12] Toll-like Receptor 2 Controls Acute Immune Complex-Driven Arthritis in Mice by Regulating the Inhibitory Fcγ Receptor IIB
Abdollahi-Roodsaz, Shahla
Koenders, Marije I.
Walgreen, Birgitte
Bolscher, Judith
Helsen, Monique M.
van den Bersselaar, Liduine A.
van Lent, Peter L.
van de Loo, Fons A. J.
van den Berg, Wim B.
ARTHRITIS AND RHEUMATISM, 2013, 65 (10): : 2583 - 2593
[13] Joint Inflammation and Chondrocyte Death Become Independent of Fcγ Receptor Type III by Local Overexpression of Interferon-γ During Immune Complex-Mediated Arthritis
Nabbe, K. C. A. M.
Boross, P.
Holthuysen, A. E. M.
Sloetjes, A. W.
Kolls, J. K.
Verbeek, S.
van Lent, P. L. E. M.
van den Berg, W. B.
ARTHRITIS AND RHEUMATISM, 2005, 52 (03): : 967 - 974
[14] HUMAN EPIDERMAL LANGERHANS CELLS SECRETE A SOLUBLE RECEPTOR FOR IGG (FC-GAMMA-RII/CD32) THAT INHIBITS THE BINDING OF IMMUNE-COMPLEXES TO FC-GAMMA-R(+) CELLS
ASTIER, A
DELASALLE, H
DELASALLE, C
BIEBER, T
ESPOSITOFARESE, ME
FREUND, M
CAZENAVE, JP
FRIDMAN, WH
TEILLAUD, JL
HANAU, D
JOURNAL OF IMMUNOLOGY, 1994, 152 (01): : 201 - 212
[15] TLR4 induced Fcγ receptor expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis:: Coupling of innate to adaptive immunity
Van Lent, P.
Blom, A.
Sloetjes, A.
Van den Berg, W.
ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 : A24 - A25
[16] FcγR expression on macrophages is related to severity and chronicity of synovial inflammation and cartilage destruction during experimental immune-complex-mediated arthritis (ICA)
Arjen B Blom
Peter L van Lent
Hanneke van Vuuren
Astrid E Holthuysen
Cor Jacobs
Leo B van de Putte
Jan G van de Winkel
Wim B van den Berg
Arthritis Research & Therapy, 2
[17] FcγR expression on macrophages is related to severity and chronicity of synovial inflammation and cartilage destruction during experimental immune-complex-mediated arthritis (ICA)
Blom, AB
van Lent, PL
van Vuuren, H
Holthuysen, AE
Jacobs, C
van de Putte, LB
van de Winkel, JG
van den Berg, WB
ARTHRITIS RESEARCH, 2000, 2 (06) : 489 - 503
[18] R406, an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation (vol 319, pg 998, 2006)
Braselmann, S.
Taylor, V
Zhao, H.
Wang, S.
Sylvain, C.
Baluom, M.
Qu, K.
Herlaar, E.
Lau, A.
Young, C.
Wong, B. R.
Lovell, S.
Sun, T.
Park, G.
Argade, A.
Jurcevic, S.
Pine, P.
Singh, R.
Grossbard, E. B.
Payan, D. G.
Masuda, E. S.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2013, 345 (02): : 326 - 326

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