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- [41] A Potent SOS1 PROTAC Degrader with Synergistic Efficacy in Combination with KRASG12C InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2024, 67 (04) : 2487 - 2511Lv, Yan论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaYang, Zixuan论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaChen, Yiming论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaMa, Xuepei论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaGuo, Mengqi论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaZhang, Chengwei论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaJiang, Xiaolin论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaWang, Chengli论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaLi, Zhuoyue论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaTai, Zhengfu论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaWang, Xiao论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaZhang, Siqi论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaMa, Shumin论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R ChinaQin, Chong论文数: 0 引用数: 0 h-index: 0机构: Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China Ocean Univ China, Ctr Targeted Prot Degradat & Drug Discovery, Qingdao 266003, Shandong, Peoples R China Pilot Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266237, Shandong, Peoples R China Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Chinese Minist Educ, Qingdao 266003, Shandong, Peoples R China
- [42] Design, Structure Optimization, and Preclinical Characterization of JAB-21822, a Covalent Inhibitor of KRASG12CJOURNAL OF MEDICINAL CHEMISTRY, 2025, 68 (03) : 2422 - 2436Li, Amin论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaLi, Sujing论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaWang, Peng论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Biol Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaDang, Chaojie论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Proc Dev Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaFan, Xinrui论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaChen, Mengran论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaLiu, Dan论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Biol Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaLi, Fu论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaLiu, Huan论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Proc Dev Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaZhang, Wei论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Hits Discovery Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaWang, Yanping论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Pharmacol Dept, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R ChinaWang, Yinxiang论文数: 0 引用数: 0 h-index: 0机构: Jacobio Pharmaceut Grp Co Ltd, Beijing 100176, Peoples R China Jacobio Pharmaceut Grp Co Ltd, Med Chem Dept, Beijing 100176, Peoples R China
- [43] Fit-for-Purpose Synthesis of a KRASG12C Covalent Inhibitor, via a Diastereoselective Hayashi ArylationORGANIC PROCESS RESEARCH & DEVELOPMENT, 2024, 28 (08) : 3313 - 3325Molinaro, Carmela论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USAWong, Nicholas论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USAWhite, Nicholas A.论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USASirois, Lauren E.论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USABigler, Raphael论文数: 0 引用数: 0 h-index: 0机构: F Hoffmann La Roche & Cie AG, Dept Proc Chem & Catalysis, Synthet Mol Tech Dev, CH-4070 Basel, Switzerland Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USABindschaedler, Quentin P.论文数: 0 引用数: 0 h-index: 0机构: F Hoffmann La Roche & Cie AG, Dept Proc Chem & Catalysis, Synthet Mol Tech Dev, CH-4070 Basel, Switzerland Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USADo, Steven论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Discovery Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USAMalhotra, Sushant论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Discovery Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USAGosselin, Francis论文数: 0 引用数: 0 h-index: 0机构: Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USA Genentech USA Inc, Dept Synthet Mol Proc Chem, South San Francisco, CA 94080 USA
- [44] Probing and overcoming KRASG12C inhibitor resistance by combination with a pan-KRAS SOS1 inhibitorCANCER RESEARCH, 2022, 82 (12)Hofmann, Marco H.论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaJurado, Sabine论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaGerlach, Daniel论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaKoga, Takamasa论文数: 0 引用数: 0 h-index: 0机构: Kindai Univ, Fac Med, Osaka, Japan Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaTrapani, Francesca论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaGmachl, Michael论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaAlpar, Donat论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaLieb, Simone论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaJeschko, Astrid论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaMitsudomi, Tetsuya论文数: 0 引用数: 0 h-index: 0机构: Kindai Univ, Fac Med, Osaka, Japan Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaKraut, Norbert论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, AustriaPetronczki, Mark P.论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria
- [45] Identification of Candidate Alterations Mediating KRASG12C Inhibitor Resistance in Advanced Colorectal and Pancreatic CancersCLINICAL CANCER RESEARCH, 2025, 31 (05) : 899 - 906Jazieh, Khalid论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USATsai, Jill论文数: 0 引用数: 0 h-index: 0机构: Guardant Hlth, Palo Alto, CA USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USASolomon, Sheila论文数: 0 引用数: 0 h-index: 0机构: Guardant Hlth, Palo Alto, CA USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USAZhu, Mojun论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USASinicrope, Frank A.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USAPedersen, Katrina S.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USAFernandez-Zapico, Martin E.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USAXie, Hao论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA Mayo Clin, Dept Oncol, 200 1st St Southwest, Rochester, MN 55905 USA
- [46] BPI-421286: A highly potent small molecule inhibitor targeting KRASG12C mutationCANCER RESEARCH, 2022, 82 (12)Zhu, Xiaoguan论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Hangzhou, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaLu, Yuan论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Hangzhou, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaGuo, Jing论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Beijing, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaYan, Dan论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Beijing, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaLi, Boyan论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Hangzhou, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaChen, Xiaoping论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Hangzhou, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaChen, Haibo论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Beijing, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaLan, Hong论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Beijing, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaWu, Hao论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Hangzhou, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaDing, Lieming论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Hangzhou, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R ChinaWang, Jiabing论文数: 0 引用数: 0 h-index: 0机构: Betta Pharmaceut Co LTD, Beijing, Peoples R China Betta Pharmaceut Co LTD, Hangzhou, Peoples R China
- [47] Exploration of a Nitromethane-Carbonylation Strategy during Route Design of an Atropisomeric KRASG12C InhibitorJOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (04): : 2075 - 2086Douglas, James J.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandTatton, Matthew R.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, Englandde Bruin, Daniel论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England Univ Utrecht, Fac Sci, Organ Chem & Catalysis, Inst Debye,Inst Nanomat Sci, NL-3584 CG Utrecht, Netherlands AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandButtar, David论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandCook, Calum论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandDai, Kuangchu论文数: 0 引用数: 0 h-index: 0机构: Changzhou SynTheAll Pharmaceut Co Ltd, Changzhou 213127, Jiangsu, Peoples R China AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandFerrer, Catalina论文数: 0 引用数: 0 h-index: 0机构: Symeres, NL-9747 AT Groningen, Netherlands AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandLeslie, Kevin论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Pharmaceut Technol & Dev Operat, Chem Dev, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandMorrison, James论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandMunday, Rachel论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Pharmaceut Technol & Dev Operat, Chem Dev, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandRonson, Thomas O.论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca, Pharmaceut Technol & Dev Operat, Chem Dev, Macclesfield SK10 2NA, Cheshire, England AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, EnglandZhao, Hucheng论文数: 0 引用数: 0 h-index: 0机构: Changzhou SynTheAll Pharmaceut Co Ltd, Changzhou 213127, Jiangsu, Peoples R China AstraZeneca, R&D, Early Chem Dev, Pharmaceut Sci, Macclesfield SK10 2NA, Cheshire, England
- [48] Synthesis of Adagrasib (MRTX849), a Covalent KRASG12C Inhibitor Drug for the Treatment of CancerORGANIC LETTERS, 2023, : 944 - 949Chen, Cheng-yi论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USALu, Zhichao论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USAScattolin, Thomas论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USAChen, Chengsheng论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USAGan, Yonghong论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USAMcLaughlin, Mark论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA Mirati Therapeut, Chem Proc R&D, San Diego, CA 92121 USA
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