Targeting aberrant splicing

被引:0
|
作者
Anna Dart
机构
[1] Nature Reviews Cancer,
来源
Nature Reviews Cancer | 2023年 / 23卷
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学科分类号
摘要
Bland et al. show that cancer types with heterozygous somatic hotspot mutations in the spliceosome component SF3B1 are vulnerable to PARP inhibition, which causes a defective response to replication stress.
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页码:653 / 653
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