Prevention of CAR-T-cell dysfunction

被引：0
|
作者：
Martin W. LaFleur
Brian C. Miller
Arlene H. Sharpe
机构：
[1] Harvard Medical School,Department of Immunology, Blavatnik Institute
[2] Evergrande Center for Immunological Diseases,Department of Medical Oncology
[3] Harvard Medical School and Brigham and Women’s Hospital,undefined
[4] Broad Institute of Harvard and Massachusetts Institute of Technology,undefined
[5] Dana-Farber Cancer Institute,undefined
来源：
Nature Biomedical Engineering | 2020年 / 4卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The overexpression of the transcription factor c-Jun improves chimeric-antigen-receptor T-cell functionality and enhances the killing of low-antigen-expressing liquid and solid cancers in mice.
引用
收藏
页码：16 / 17
页数：1
相关论文
共 50 条
  • [1] Prevention of CAR-T-cell dysfunction
    LaFleur, Martin W.
    Miller, Brian C.
    Sharpe, Arlene H.
    [J]. NATURE BIOMEDICAL ENGINEERING, 2020, 4 (01) : 16 - 17
  • [2] Improving the safety of CAR-T-cell therapy: The risk and prevention of viral infection for patients with relapsed or refractory B-cell lymphoma undergoing CAR-T-cell therapy
    Qian, Hu
    Yang, Xingcheng
    Zhang, Tingting
    Zou, Ping
    Zhang, Yicheng
    Tian, Weiwei
    Mao, Zekai
    Wei, Jia
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 2024, 99 (04) : 662 - 678
  • [3] Application of nanotechnology in CAR-T-cell immunotherapy
    Qiang Zeng
    Zhigang Liu
    Ting Niu
    Chuan He
    Ying Qu
    Zhiyong Qian
    [J]. Chinese Chemical Letters, 2023, 34 (03) : 78 - 94
  • [4] Application of nanotechnology in CAR-T-cell immunotherapy
    Zeng, Qiang
    Liu, Zhigang
    Niu, Ting
    He, Chuan
    Qu, Ying
    Qian, Zhiyong
    [J]. CHINESE CHEMICAL LETTERS, 2023, 34 (03)
  • [5] CAR-T-cell neurotoxicity: hope is on the horizon
    Ahmed, Omar
    [J]. BLOOD, 2019, 133 (20) : 2114 - 2116
  • [6] Dynamic imaging for CAR-T-cell therapy
    Emami-Shahri, Nia
    Papa, Sophie
    [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 2016, 44 : 386 - 390
  • [7] Advances in CAR-T-cell therapy in T-cell malignancies
    Zheng, Rubing
    Zhu, Xiaojian
    Xiao, Yi
    [J]. JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 17 (01)
  • [8] Inertial Microfluidic Purification of CAR-T-Cell Products
    Elsemary, Mona T.
    Maritz, Michelle F.
    Smith, Louise E.
    Warkiani, Majid
    Bandara, Veronika
    Napoli, Silvana
    Barry, Simon C.
    Coombs, Justin T.
    Thierry, Benjamin
    [J]. ADVANCED BIOLOGY, 2022, 6 (01):
  • [9] outlook A solid start for CAR-T-cell therapy
    Dolgin, Elie
    [J]. NATURE, 2022, 612 (7941) : S50 - S52
  • [10] T-cell exhaustion in CAR-T-cell therapy and strategies to overcome it
    Yin, Xuechen
    He, Lingfeng
    Guo, Zhigang
    [J]. IMMUNOLOGY, 2023, 169 (04) : 400 - 411
12345