Function and dysfunction of presenilin in Alzheimer’s disease

被引：0
|
作者：
Jie Shen
机构：
[1] Harvard Medical School,
来源：
Molecular Neurodegeneration | / 8卷 / Suppl 1期
关键词：
Dementia; Missense Mutation; Mutant Mouse; Mutant Protein; Major Gene;
D O I：
10.1186/1750-1326-8-S1-O11
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Presenilin transgenic mice as models of Alzheimer's disease
    Elder, Gregory A.
    Sosa, Miguel A. Gama
    De Gasperi, Rita
    Dickstein, Dara L.
    Hof, Patrick R.
    BRAIN STRUCTURE & FUNCTION, 2010, 214 (2-3): : 127 - 143
  • [32] Presenilin-1 mutations in Alzheimer's disease
    C. Russo
    G. Schettini
    T. C. Saido
    C. Hulette
    C. Lippa
    L. Lannfelt
    B. Ghetti
    P. Gambetti
    M. Tabaton
    J. K. Teller
    Nature, 2000, 405 : 531 - 532
  • [33] Polymorphisms in the presenilin 1 and presenilin 2 genes and risk for sporadic Alzheimer's disease
    Combarros, O
    Alvarez-Arcaya, A
    Oterino, A
    Berciano, J
    Delgado-Rodríguez, M
    Peña, N
    Fernández-Viadero, C
    Pérez-López, JL
    Setién, S
    Carvajal, A
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 1999, 171 (02) : 88 - 91
  • [34] Loss of presenilin function causes Alzheimer's disease-like neuro degeneration in the mouse
    Chen, Qian
    Nakajima, Akira
    Choi, Se Hoon
    Xiong, Xiaoli
    Tang, Ya-Ping
    JOURNAL OF NEUROSCIENCE RESEARCH, 2008, 86 (07) : 1615 - 1625
  • [35] Plaque pathology in presenilin-1 Alzheimer's disease
    Shepherd, C
    Gregory, G
    McCann, H
    Halliday, G
    Kwok, J
    Schofield, P
    Kril, J
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S220 - S220
  • [36] Neurobiology - Presenilin-1 mutations in Alzheimer's disease
    Russo, C
    Schettini, G
    Saido, TC
    Hulette, C
    Lippall, C
    Lannfelt, L
    Ghetti, B
    Gambetti, P
    Tabaton, M
    Teller, JK
    NATURE, 2000, 405 (6786) : 531 - 532
  • [37] A presenilin 1 mutation in the first case of Alzheimer's disease
    Mueller, Ulrich
    Winter, Pia
    Graeber, Manuel B.
    LANCET NEUROLOGY, 2013, 12 (02): : 129 - 130
  • [38] Presenilin mutations and their impact on neuronal differentiation in Alzheimer's disease
    Hernandez-Sapiens, Mercedes A.
    Reza-Zaldivar, Edwin E.
    Marquez-Aguirre, Ana L.
    Gomez-Pinedo, Ulises
    Matias-Guiu, Jorge
    Cevallos, Ricardo R.
    Mateos-Diaz, Juan C.
    Sanchez-Gonzalez, Victor J.
    Canales-Aguirre, Alejandro A.
    NEURAL REGENERATION RESEARCH, 2022, 17 (01) : 31 - 37
  • [39] Screening for mutation of the presenilin 2 gene in Alzheimer's disease
    Isoe, K
    Urakami, K
    Wakutani, Y
    Yong, J
    Adachi, Y
    Nakashima, K
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 1997, 8 (01) : 60 - 60
  • [40] Presenilin-1 gene mutations in Alzheimer's disease
    Mann, DMA
    BRAIN PATHOLOGY, 2000, 10 (04) : 713 - 713
12345