microRNA-34a inhibits epithelial mesenchymal transition in human cholangiocarcinoma by targeting Smad4 through transforming growth factor-beta/Smad pathway

被引：0
|
作者：
Pengfei Qiao
Guodong Li
Wen Bi
Lianmeng Yang
Lei Yao
Dequan Wu
机构：
[1] the Second Affiliated Hospital of Harbin Medical University,Department of General Surgery
[2] the Fourth Affiliated Hospital of Harbin Medical University,Department of General Surgery
[3] the Fourth Affiliated Hospital of Harbin Medical University,Bio
来源：
BMC Cancer | / 15卷
关键词：
Cholangiocarcinoma; miR-34a; Smad4; Epithelial-mesenchymal transition; Transforming growth factor-beta;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Hepatitis B Virus Regulates Apoptosis and Tumorigenesis through the MicroRNA-15a-Smad7-Transforming Growth Factor Beta Pathway
    Liu, Ningning
    Jiao, Tong
    Huang, Yan
    Liu, Wenjun
    Li, Zhiwei
    Ye, Xin
    JOURNAL OF VIROLOGY, 2015, 89 (05) : 2739 - 2749
  • [42] The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β
    Tojo, M
    Hamashima, Y
    Hanyu, A
    Kajimoto, T
    Saitoh, M
    Miyazono, K
    Node, M
    Imamura, T
    CANCER SCIENCE, 2005, 96 (11): : 791 - 800
  • [43] Smad4 overexpression in hepatocellular carcinoma is strongly associated with transforming growth factor beta II receptor immunolabeling
    Torbenson, M
    Marinopoulos, S
    Dang, DT
    Choti, M
    Ashfaq, R
    Maitra, A
    Boitnott, J
    Wilentz, RE
    HUMAN PATHOLOGY, 2002, 33 (09) : 871 - 876
  • [44] Icariin alleviates transforming growth factor-β1-induced epithelial-mesenchymal transition by targeting Smad and MAPK signaling pathways
    Li, Zhuying
    Yuan, Xingxing
    Wang, Bingyu
    Gao, Fengli
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2020, 12 (02): : 343 - 360
  • [45] Involvement of Smad4, but not of Smad2, in transforming growth factor-beta1-induced trophoblast expression of matrix metalloproteinase-2
    Lin, HY
    Yang, Q
    Wang, HM
    Qi, JG
    Zhang, H
    Wang, HX
    Tsang, BK
    Zhu, C
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2006, 11 : 637 - 646
  • [46] Products Of Heme Oxygenase Attenuate Transforming Growth Factor-Beta Mediated Lung Epithelial Mesenchymal Transition
    Dias, A.
    Visner, G.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 183
  • [47] Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial-mesenchymal transition in proliferative vitreoretinopathy
    Pao, Shu-, I
    Lin, Le-Tien
    Chen, Yi-Hao
    Chen, Ching-Long
    Chen, Jiann-Torng
    PLOS ONE, 2021, 16 (08):
  • [48] Loss of Transforming Growth Factor Beta/SMAD Function Induces Interleukin1α to Mediate Epithelial-to-Mesenchymal Transition in Pancreatic Cancer
    Dosch, Austin R.
    Messaggio, Fanuel
    Gaidarski, Alexander
    Dai, Xizi
    VanSaun, Michael N.
    Nagathihalli, Nagaraj
    Merchant, Nipun B.
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2018, 227 (04) : S241 - S242
  • [49] The transforming growth factor beta 1/SMAD signaling pathway involved in human chronic myeloid leukemia
    Su, Enyu
    Han, Xiao
    Jiang, Guosheng
    TUMORI JOURNAL, 2010, 96 (05): : 659 - 666
  • [50] MicroRNA-224 Is Involved in Transforming Growth Factor-β-Mediated Mouse Granulosa Cell Proliferation and Granulosa Cell Function by Targeting Smad4
    Yao, Guidong
    Yin, Mianmian
    Lian, Jie
    Tian, Hui
    Liu, Lin
    Li, Xin
    Sun, Fei
    MOLECULAR ENDOCRINOLOGY, 2010, 24 (03) : 540 - 551
12345