Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning

被引:0
|
作者
Nagendran Muthusamy
Xuying Zhang
Caroline A Johnson
Prem N Yadav
H Troy Ghashghaei
机构
[1] College of Veterinary Medicine,Department of Molecular Biomedical Sciences
[2] North Carolina State University,Division of Pharmacology
[3] CSIR–Central Drug Research Institute,undefined
来源
Nature Neuroscience | 2017年 / 20卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
In this study, the authors reveal distinct developmental programs underlying innate and learned olfactory behaviors by demonstrating that chemogenetic inactivation of neurons generated in neonatal mice impairs the behavioral response to aversive odorants, whereas inactivation of adult-born neurons impairs learning of novel food-related odors.
引用
收藏
页码:20 / 23
页数:3
相关论文
共 50 条
  • [31] Neuromodulation in circuits of aversive emotional learning
    Likhtik, Ekaterina
    Johansen, Joshua P.
    NATURE NEUROSCIENCE, 2019, 22 (10) : 1586 - 1597
  • [32] Neuromodulation in circuits of aversive emotional learning
    Ekaterina Likhtik
    Joshua P. Johansen
    Nature Neuroscience, 2019, 22 : 1586 - 1597
  • [33] Pallidal circuits for aversive motivation and learning
    Stephenson-Jones, Marcus
    CURRENT OPINION IN BEHAVIORAL SCIENCES, 2019, 26 : 82 - 89
  • [34] Two Insulin-like Peptides Antagonistically Regulate Aversive Olfactory Learning in C. elegans
    Chen, Zhunan
    Hendricks, Michael
    Cornils, Astrid
    Maier, Wolfgang
    Alcedo, Joy
    Zhang, Yun
    NEURON, 2013, 77 (03) : 572 - 585
  • [35] Redundant neural circuits regulate olfactory integration
    Yang, Wenxing
    Wu, Taihong
    Tu, Shasha
    Qin, Yuang
    Shen, Chengchen
    Li, Jiangyun
    Choi, Myung-Kyu
    Duan, Fengyun
    Zhang, Yun
    PLOS GENETICS, 2022, 18 (01):
  • [36] The carrot, not the stick:: appetitive rather than aversive gustatory stimuli support associative olfactory learning in individually assayed Drosophila larvae
    Hendel, T
    Michels, B
    Neuser, K
    Schipanski, A
    Kaun, K
    Sokolowski, M
    Marohn, F
    Michel, R
    Heisenberg, M
    Gerber, B
    JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 2005, 191 (03): : 265 - 279
  • [37] The carrot, not the stick: appetitive rather than aversive gustatory stimuli support associative olfactory learning in individually assayed Drosophila larvae
    Thomas Hendel
    Birgit Michels
    Kirsa Neuser
    Angela Schipanski
    Karla Kaun
    Marla B. Sokolowski
    Frank Marohn
    René Michel
    Martin Heisenberg
    Bertram Gerber
    Journal of Comparative Physiology A, 2005, 191 : 265 - 279
  • [38] Olfactory modulation by dopamine in the context of aversive learning
    Dacks, Andrew M.
    Riffell, Jeffrey A.
    Martin, Joshua P.
    Gage, Stephanie L.
    Nighorn, Alan J.
    JOURNAL OF NEUROPHYSIOLOGY, 2012, 108 (02) : 539 - 550
  • [39] An appetitive olfactory learning paradigm for zebrafish in their home tanks
    Doyle, Jillian M.
    Fine, Alan
    Croll, Roger P.
    BEHAVIOURAL BRAIN RESEARCH, 2025, 485
  • [40] A Drosophila ex vivo model of olfactory appetitive learning
    Suzuki-Sawano, Ema
    Ueno, Kohei
    Naganos, Shintaro
    Sawano, Yoshihiro
    Horiuchi, Junjiro
    Saitoe, Minoru
    SCIENTIFIC REPORTS, 2017, 7