Pharmacokinetics and Safety of Single and Multiple Doses of Oral N-Acetylcysteine in Healthy Chinese and Caucasian Volunteers: An Open-Label, Phase I Clinical Study

被引：0
|
作者：
Alberto Papi
Andrea F. D. Di Stefano
Milko Radicioni
机构：
[1] University of Ferrara,Division of Internal and Cardiorespiratory Medicine, Department of Medical Sciences
[2] CROSS Research S.A.,undefined
来源：
Advances in Therapy | 2021年 / 38卷
关键词：
Caucasian; Chinese; Healthy volunteer; -acetylcysteine; Pharmacokinetics; Phase I;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：468 / 478
页数：10
相关论文
共 50 条
  • [31] Pharmacokinetics and safety of transdermal and oral granisetron in healthy Chinese subjects: An open-label, randomized, crossover study
    Chen, Rui
    Chen, Xia
    Wang, Hongyun
    Zhong, Wen
    Oh, Eun Sil
    Park, Min Soo
    Kumagai, Yuji
    Zhou, Li
    Nagahama, Fumiko
    Hu, Pei
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2019, 57 (01) : 24 - 31
  • [32] Safety and Clinical Pharmacokinetics of Nemonoxacin, a Novel Non-Fluorinated Quinolone, in Healthy Chinese Volunteers Following Single and Multiple Oral Doses
    Guo, Beining
    Wu, Xiaojie
    Zhang, Yingyuan
    Shi, Yaoguo
    Yu, Jicheng
    Cao, Guoying
    Zhang, Jing
    CLINICAL DRUG INVESTIGATION, 2012, 32 (07) : 475 - 486
  • [33] Safety and Clinical Pharmacokinetics of Nemonoxacin, a Novel Non-Fluorinated Quinolone, in Healthy Chinese Volunteers Following Single and Multiple Oral Doses
    Beining Guo
    Xiaojie Wu
    Yingyuan Zhang
    Yaoguo Shi
    Jicheng Yu
    Guoying Cao
    Jing Zhang
    Clinical Drug Investigation, 2012, 32 (7) : 475 - 486
  • [34] Multiple rising doses of oral BI 1358894 in healthy male volunteers: a phase I study investigating safety, tolerability and pharmacokinetics
    Goettel, M.
    Fuertig, R.
    Wiebe, S.
    Herich, L.
    Sharma, V.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2020, 40 : S254 - S255
  • [35] Pharmacokinetics and tolerability of intravenous posaconazole in healthy Chinese volunteers: a randomized, open-label and single-dose study
    Ji, Wei
    Zhao, Hengli
    Yang, Shaomei
    Wen, Qing
    He, Kun
    PHARMAZIE, 2020, 75 (10): : 491 - 493
  • [36] A PHASE 1, OPEN-LABEL STUDY TO EVALUATE THE PHARMACOKINETICS OF A SINGLE DOSE OF DAZODALIBEP IN HEALTHY JAPANESE AND CAUCASIAN PARTICIPANTS
    Der, K.
    Wang, Z.
    Bosoro, L.
    Hewitt, L.
    Wilson, T.
    Huang, J.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2024, 115 : S79 - S79
  • [37] A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of V-7404 in Healthy Adult Volunteers
    Kankam, Martin K.
    Burns, Jennifer M.
    Collett, Marc S.
    Corrado, Michael L.
    Hincks, Jeffrey R.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (10)
  • [38] An open-label phase 1 study to evaluate the pharmacokinetics of axitinib (AG-013736) in healthy Chinese volunteers
    Chen, Ying
    Jiang, Ji
    Zhang, Jianyan
    Tortorici, Michael
    Pithavala, Yazdi K.
    Lu, Lei
    Ni, Grace
    Hu, Pei
    CANCER RESEARCH, 2010, 70
  • [39] Pharmacokinetics of Rasagiline in Healthy Adult Chinese Volunteers with Various Genotypes: A Single-Center, Open-Label, Multiple-Dose Study
    Xia Chen
    Qian Zhao
    Ji Jiang
    Jian Liu
    Pei Hu
    Clinical Drug Investigation, 2016, 36 : 369 - 376
  • [40] Pharmacokinetics of Rasagiline in Healthy Adult Chinese Volunteers with Various Genotypes: A Single-Center, Open-Label, Multiple-Dose Study
    Chen, Xia
    Zhao, Qian
    Jiang, Ji
    Liu, Jian
    Hu, Pei
    CLINICAL DRUG INVESTIGATION, 2016, 36 (05) : 369 - 376
12345