Implications of cancer evolution for drug development

被引：0

作者：

Samra Turajlic

Charles Swanton

机构：

[1] Translational Cancer Therapeutics Laboratory,

[2] The Francis Crick Institute,undefined

[3] Renal and Skin Units,undefined

[4] The Royal Marsden Hospital,undefined

[5] Cancer Research UK Lung Cancer Centre of Excellence,undefined

[6] University College London Cancer Institute,undefined

来源：

Nature Reviews Drug Discovery | 2017年 / 16卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Tumour evolution, which results in the existence of multiple distinct populations of cancer cells within the same tumour and the same patient, is increasingly appreciated to have a key role in drug resistance. In this article, we discuss the implications for drug development, including approaches to reduce the likelihood of the emergence of drug resistance.

引用

页码：441 / 442

页数：1

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