Therapeutic decision-making for patients with fluctuating mitral regurgitation

Mitral regurgitation (MR) often varies dynamically with changes in loading conditionsDynamic fluctuation of MR can precipitate symptoms and induce left ventricular remodelling, and might have prognostic valueAn intermittent increase in MR is often accompanied by dynamic pulmonary hypertensionThe optimal treatment strategy for fluctuating MR is uncertain, but can include a combination of surgery, cardiac resynchronization therapy, and new mitral valve approaches