Fit-for-Purpose Immunohistochemical Biomarkers

被引:0
|
作者
Emina Emilia Torlakovic
机构
[1] University of Saskatchewan,Department of Pathology and Laboratory Medicine, College of Medicine
[2] and Saskatchewan Health Authority,Department of Pathology and Laboratory Medicine
[3] Royal University Hospital,undefined
来源
Endocrine Pathology | 2018年 / 29卷
关键词
Immunohistochemistry; Biomarkers; Quality assurance; Validation;
D O I
暂无
中图分类号
学科分类号
摘要
There are two aspects of immunohistochemistry (IHC) that are relevant to practicing pathologist: (1) understanding of IHC biomarker panels that are suitable for diagnostic, prognostic and predictive testing, and (2) understanding of IHC quality assurance (QA), which makes sure that the tests in these panels work as they should. The two aspects are closely linked together and call for collaborative approach between pathologists and IHC laboratory technologists as both need to be involved in developing and maintaining IHC biomarkers that are “fit-for-purpose”. This article reviews the most current IHC QA concepts that are imminently material to practicing pathologists with emphasis on challenges that are specific to endocrine pathology.
引用
收藏
页码:199 / 205
页数:6
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