Economic Impact and Long-Term Graft Outcomes of Mycophenolate Mofetil Dosage Modifications Following Gastrointestinal Complications in Renal Transplant Recipients

被引:0
|
作者
Gerardo Machnicki
Jean-Francois Ricci
Daniel C. Brennan
Mark A. Schnitzler
机构
[1] Novartis Pharmaceuticals,Department of Medicine
[2] Novartis Pharma AG,Center for Outcomes Research
[3] Washington University School of Medicine,undefined
[4] Saint Louis University School of Medicine,undefined
[5] Saint Louis University School of Medicine (SLUCOR),undefined
来源
PharmacoEconomics | 2008年 / 26卷
关键词
Graft Failure; Mycophenolate Mofetil; Graft Loss; United States Renal Data System; Functioning Graft;
D O I
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中图分类号
学科分类号
摘要
Introduction: Gastrointestinal (GI) complications are common following renal transplantation. Discontinuing or reducing the dosage of mycophenolate mofetil can improve GI tolerability but adversely affect graft outcomes. This analysis was undertaken to assess the 3-year economic and clinical impact of mycophenolate mofetil dosage modifications or discontinuation following post-transplant GI events compared with no dosage modification.
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页码:951 / 967
页数:16
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