Molecular-genetic mechanisms of cornea morphogenesis

被引：0
|
作者：
I. G. Panova
Yu. V. Markitantova
Yu. A. Smirnova
R. D. Zinovieva
机构：
[1] Russian Academy of Sciences,Koltzov Institute of Developmental Biology
来源：
Biology Bulletin | 2015年 / 42卷
关键词：
Biology Bulletin; Corneal Epithelium; Poly Merase Chain Reaction; Corneal Stroma; PAX6 Gene;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this paper, we analyzed our own results and published data on the expression of regulatory genes encoding transcription factors Pax6/PAX6, Pitx2/PITX2, Fox1/FOXC1, Prox1/PROX1, Oct4/OCT4, Nanog/NANOG, and TGFβ2 signaling protein during morphogenesis of the cornea in vertebrates. We considered the results obtained for the cornea of model animals, primarily mice, and human fetal cornea. The main possibility of establishing common mechanisms of eye development in vertebrates in health and disease is comparative studies of eye morphogenesis of humans and animal models.
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页码：83 / 91
页数：8
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