Solubility of ibuprofen in supercritical carbon dioxide

被引:0
|
作者
I. V. Kuznetsova
I. I. Gilmutdinov
I. M. Gilmutdinov
A. A. Mukhamadiev
A. N. Sabirzyanov
机构
[1] Kazan National Research Technological University,
关键词
solubility; anthracene; ibuprofen; supercritical fluid; Peng-Robinson equation of state;
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摘要
An experimental apparatus that allows measurement of solubility of solid compounds and liquids in supercritical (SC) fluids in a wide range of temperatures and pressures using a dynamic method is constructed. Experimental data on the solubility of anthracene at 318.1 and 328.1 K and results of the solubility of ibuprofen at 313, 323, and 333 K at 10–30 MPa are obtained. The solubility of ibuprofen in SC CO2 is described using the Peng-Robinson equation of state. Parameters of binary interactions are obtained for the ibuprofen-supercritical CO2 system.
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页码:814 / 819
页数:5
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