Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

被引：0
|
作者：
Corinne Benakis
David Brea
Silvia Caballero
Giuseppe Faraco
Jamie Moore
Michelle Murphy
Giulia Sita
Gianfranco Racchumi
Lilan Ling
Eric G Pamer
Costantino Iadecola
Josef Anrather
机构：
[1] Feil Family Brain and Mind Research Institute,
[2] Weill Cornell Medical College,undefined
[3] Immunology Program and Infectious Disease Service,undefined
[4] Memorial Sloan Kettering Cancer Center,undefined
[5] Immunology and Microbial Pathogenesis Program,undefined
[6] Weill Cornell Graduate School of Medical Sciences,undefined
[7] Lucille Castori Center for Microbes,undefined
[8] Inflammation and Cancer,undefined
[9] Memorial Sloan Kettering Cancer Center,undefined
来源：
Nature Medicine | 2016年 / 22卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Alterations in the gut microbiota affect stroke outcomes via modulation of T cells, suggesting a gut-brain axis linking commensal microbes with the CNS.
引用
收藏
页码：516 / 523
页数：7
相关论文
共 50 条
  • [31] T cells and intestinal commensal bacteria-ignorance, rejection, and acceptance
    Chai, Jiani N.
    Zhou, You W.
    Hsieh, Chyi-Song
    [J]. FEBS LETTERS, 2014, 588 (22) : 4167 - 4175
  • [32] Intestinal Intraepithelial TCRγδ+ T Cells are Activated by Normal Commensal Bacteria
    Jeong, Sang Phil
    Kang, Jung-Ah
    Park, Sung-Gyoo
    [J]. JOURNAL OF MICROBIOLOGY, 2012, 50 (05) : 837 - 841
  • [33] Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
    Cebula, Anna
    Seweryn, Michal
    Rempala, Grzegorz A.
    Pabla, Simarjot Singh
    McIndoe, Richard A.
    Denning, Timothy L.
    Bry, Lynn
    Kraj, Piotr
    Kisielow, Pawel
    Ignatowicz, Leszek
    [J]. NATURE, 2013, 497 (7448) : 258 - +
  • [34] Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
    Anna Cebula
    Michal Seweryn
    Grzegorz A. Rempala
    Simarjot Singh Pabla
    Richard A. McIndoe
    Timothy L. Denning
    Lynn Bry
    Piotr Kraj
    Pawel Kisielow
    Leszek Ignatowicz
    [J]. Nature, 2013, 497 : 258 - 262
  • [35] The role of T cells in acute ischemic stroke
    Wang, Yi-Ran
    Cui, Wen-Qiang
    Wu, Hong-Yun
    Xu, Xiang-Dong
    Xu, Xiang-Qing
    [J]. BRAIN RESEARCH BULLETIN, 2023, 196 : 20 - 33
  • [36] Electro-acupuncture treatment inhibits the inflammatory response by regulating ?? T and Treg cells in ischemic stroke
    Wang, Yaling
    Chen, Yonglin
    Meng, Lingling
    Wu, Bufan
    Ouyang, Ling
    Peng, Rou
    Hou, Dan
    Liu, Sitong
    Lu, Shengfeng
    Jing, Xinyue
    Fu, Shuping
    Xu, Bin
    [J]. EXPERIMENTAL NEUROLOGY, 2023, 362
  • [37] Choice of antiplatelet therapy affects mortality outcome in ischemic stroke - a cohort study
    Barlas, R.
    Loke, Y.
    Mamas, M.
    Bettencourt-Silva, J.
    Ford, I.
    Clark, A.
    Bowles, K.
    Metcalf, A.
    Potter, J.
    Myint, P.
    [J]. CEREBROVASCULAR DISEASES, 2018, 45 : 251 - 251
  • [38] Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota
    Fujiwara, Daisuke
    Wei, Bo
    Presley, Laura L.
    Brewer, Sarah
    McPherson, Michael
    Lewinski, Michael A.
    Borneman, James
    Braun, Jonathan
    [J]. JOURNAL OF IMMUNOLOGY, 2008, 180 (09): : 5843 - 5852
  • [39] Systemic control of plasmacytoid dendritic cells by CD8+T cells and commensal microbiota
    Fujiwara, Daisuke
    Wei, Bo
    Presley, Laura L.
    Brewer, Sarah N.
    McPherson, Michael
    Borneman, James
    Braun, Jonathan
    [J]. GASTROENTEROLOGY, 2008, 134 (04) : A43 - A43
  • [40] Role of commensal microbiota and CD8+T cells in formation of invariant NKT cells
    Wei, Bo
    Fujiwara, Daisuke
    Brewer, Sarah
    McPherson, Michael
    Kronenberg, Mitchell
    Braun, Jonathan
    [J]. JOURNAL OF IMMUNOLOGY, 2006, 176 : S71 - S71
12345