PNIPAAm-b-PPG-b-PNIPAAm triblock copolymers were prepared by redox polymerization. The self-assembly behavior and thermosensitive property of the copolymers in water were studied using 1H-NMR, TEM and a UV spectrophotometer. The results showed that the LCST of the copolymers was 32 °C, which was consistent with that of pure PNIPAAm. The copolymers could form a vesicular structure in an aqueous solution by self-assembly. The hollow structure of the PNIPAAm-b-PPG-b-PNIPAAm vesicles combined with the temperature-sensitive property may enable many potential applications of the vesicles.
机构:
McMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, CanadaMcMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, Canada
Xu, Rui
Dehghan, Ashkan
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McMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, CanadaMcMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, Canada
Dehghan, Ashkan
Shi, An-Chang
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McMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, CanadaMcMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, Canada
Shi, An-Chang
Zhou, Jiajia
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Beihang Univ, Ctr Soft Matter Phys & Its Applicat, Beijing 100191, Peoples R China
Beihang Univ, Minist Educ, Sch Chem, Key Lab Bioinspired Smart Interfacial Sci & Techn, Beijing 100191, Peoples R China
Beihang Univ, Beijing Adv Innovat Ctr Biomed Engn, Beijing 100191, Peoples R ChinaMcMaster Univ, Dept Phys & Astron, 1280 Main St West, Hamilton, ON L8S 4M1, Canada
机构:
Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Araste, Fatemeh
Aliabadi, Ali
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Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Aliabadi, Ali
Abnous, Khalil
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Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Abnous, Khalil
Taghdisi, Seyed Mohammad
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Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Taghdisi, Seyed Mohammad
Ramezani, Mohammad
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Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Ramezani, Mohammad
Alibolandi, Mona
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Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran