Emerging NIR-II Luminescent Gold Nanoclusters for In Vivo Bioimaging

被引:0
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作者
Siqi Ni
Yizhuo Liu
Shufen Tong
Shihua Li
Xiaorong Song
机构
[1] Fuzhou University,MOE Key Laboratory for Analytical Science of Food Safety and Biology, Engineering Technology Research Center on Reagent and Instrument for Rapid Detection of Product Quality and Food Safety in Fujian Province, College of Chemistry
[2] Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China,undefined
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Gold nanoclusters; NIR-II; Fluorescent probe; In vivo imaging; Bioimaging;
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摘要
Gold nanoclusters (AuNCs) with near-infrared II (NIR-II) photoluminescence (PL) have emerged as novel bioimaging probes for in vivo disease diagnosis. So far, it still lacks a systematic review focusing on the synthesis, PL tuning, and in vivo imaging of NIR-II luminescent AuNCs. In this review, we briefly introduce the synthesis of NIR-II luminescent AuNCs using various surface ligands. We discuss the origins and properties of NIR-II PL in AuNCs, and summarize the strategies for improving and/or tuning NIR-II PL emissions. We also provide an overview of the recent progress in the application of AuNCs in tumor-targeted imaging, molecular imaging, and other areas (such as the sensitive imaging of bones, vessels, lymph nodes, etc.). Finally, we present the prospects and challenges in the field of NIR-II luminescent AuNCs and related imaging applications, expecting to offer comprehensive understanding of this field, and thereby deepening and broadening the biological application of AuNCs.
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页码:260 / 271
页数:11
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