Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress

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作者
Joelle A. Desmarais
Christian Unger
Ivan Damjanov
Mark Meuth
Peter Andrews
机构
[1] University of Sheffield,Centre for Stem Cell Biology, Department of Biomedical Science
[2] University of Sheffield,Institute for Cancer Studies, Department of Oncology, School of Medicine
[3] University of Kansas Hospital,Department of Pathology
关键词
Induced pluripotent stem cells; Integration-free reprogramming; Checkpoint kinase 1; Apoptosis; Replication stress; Ataxia telangiectasia and rad3-related; Ataxia telangiectasia mutated; Genomic instability;
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