Synthetic transformations of higher terpenoids: XXIV. Synthesis of cyanoethyl derivatives of lupane triterpenoids and their transformation into 1,2,4-oxadiazoles

被引：0
|
作者：
A. N. Antimonova
N. V. Uzenkova
N. I. Petrenko
M. M. Shakirov
E. E. Shul’ts
G. A. Tolstikov
机构：
[1] Russian Academy of Sciences,Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Division
来源：
Russian Journal of Organic Chemistry | 2011年 / 47卷
关键词：
Oxime; Acrylonitrile; Betulinic Acid; Betulin; Betulonic Acid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cyanoethylation of lupane triterpenoids was performed. Amide oximes of 3β-O-(2-cyanoethyl)-betulinic acid methyl ester and 3β-O-acetyl-28-O-(2-cyanoethyl)betulin and the corresponding O-[2-(1,2,4-oxadiazol-3-yl)ethyl] lupane derivatives were obtained.
引用
收藏
相关论文
共 50 条
  • [41] Recent advances in the synthesis of 1,2,4-and 1,3,4-oxadiazoles
    Jakopin, Ziga
    Dolenc, Marija Sollner
    CURRENT ORGANIC CHEMISTRY, 2008, 12 (10) : 850 - 898
  • [42] Synthesis and characteristics of novel, high-nitrogen 1,2,4-oxadiazoles
    Fu, Zhanda
    Wang, Yang
    Yang, Li
    Su, Rui
    Chen, Jun
    Nie, Fude
    Huang, Jinglun
    Chen, Fu-Xue
    RSC ADVANCES, 2014, 4 (23) : 11859 - 11861
  • [43] Furanolabdanoid-based 1,2,4-oxadiazoles: Synthesis and cytotoxic activity
    Mironov, Maxim E.
    Pokrovsky, Mikhail A.
    Kharitonov, Yurii V.
    Shakirov, Makhmut M.
    Pokrovsky, Andrey G.
    Shults, Elvira E.
    CHEMISTRYSELECT, 2016, 1 (03): : 417 - 424
  • [44] THE SYNTHESIS OF 3,5-DIAMINO-1,2,4-OXADIAZOLES .1.
    TILLEY, JW
    RAMUZ, H
    HELVETICA CHIMICA ACTA, 1980, 63 (04) : 832 - 840
  • [45] Synthesis and In vitro Antibacterial Activity of Some 1,2,4-triazoles and 1,3,4-oxadiazoles Derivatives
    Socea, Laura-Ileana
    Saramet, Gabriel
    Dinu-Pirvu, Cristina Elena
    Draghici, Constantin
    Socea, Bogdan
    REVISTA DE CHIMIE, 2014, 65 (03): : 253 - 256
  • [46] SYNTHESIS OF FURYL-SUBSTITUTED ISOXAZOLES, ISOXAZOLINES, AND 1,2,4-OXADIAZOLES
    JEDLOVSKA, E
    FISERA, L
    CHEMICAL PAPERS, 1992, 46 (01): : 42 - 46
  • [47] HYDROXYLAMINE DERIVATIVES AS POTENTIAL ANTIMALARIAL AGENTS .3. 1,2,4-OXADIAZOLES
    HYNES, JB
    GRATZ, RF
    JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (11) : 1198 - &
  • [48] SYNTHESIS OF SUBSTITUTED 1,2,4-OXADIAZOLES, ISOXAZOLES AND 1,2,4-TRIAZOLES FROM NITRILOXIDES AND AZOMETHINIMINES
    RIED, W
    FULDE, M
    CHEMIKER-ZEITUNG, 1989, 113 (10): : 315 - 319
  • [49] RING TRANSFORMATIONS OF HETEROCYCLES .1. TRANSFORMATION OF 4-AMINO-DELTA-2-1,2,4-OXADIAZOLINES INTO 1,3,4-OXADIAZOLES
    ELABADELAH, MM
    NAZER, MZ
    HUSSEIN, AQ
    AWADALLAH, AM
    RADEMACHER, P
    WOYDT, M
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1991, 28 (05) : 1229 - 1234
  • [50] A NOVEL RING TRANSFORMATION - 1,2,4-OXADIAZOLES FROM PYRIMIDINE-N-OXIDES
    KORBONITS, D
    SIMON, K
    KOLONITS, P
    TETRAHEDRON LETTERS, 1983, 24 (51) : 5763 - 5766
12345