Synthetic transformations of higher terpenoids: XXIV. Synthesis of cyanoethyl derivatives of lupane triterpenoids and their transformation into 1,2,4-oxadiazoles

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作者
A. N. Antimonova
N. V. Uzenkova
N. I. Petrenko
M. M. Shakirov
E. E. Shul’ts
G. A. Tolstikov
机构
[1] Russian Academy of Sciences,Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Division
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Oxime; Acrylonitrile; Betulinic Acid; Betulin; Betulonic Acid;
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摘要
Cyanoethylation of lupane triterpenoids was performed. Amide oximes of 3β-O-(2-cyanoethyl)-betulinic acid methyl ester and 3β-O-acetyl-28-O-(2-cyanoethyl)betulin and the corresponding O-[2-(1,2,4-oxadiazol-3-yl)ethyl] lupane derivatives were obtained.
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