Common genetic variants influence human subcortical brain structures

被引：0

作者：

Derrek P. Hibar

Jason L. Stein

Miguel E. Renteria

Alejandro Arias-Vasquez

Sylvane Desrivières

Neda Jahanshad

Roberto Toro

Katharina Wittfeld

Lucija Abramovic

Micael Andersson

Benjamin S. Aribisala

Nicola J. Armstrong

Manon Bernard

Marc M. Bohlken

Marco P. Boks

Janita Bralten

Andrew A. Brown

M. Mallar Chakravarty

Qiang Chen

Christopher R. K. Ching

Gabriel Cuellar-Partida

Anouk den Braber

Sudheer Giddaluru

Aaron L. Goldman

Oliver Grimm

Tulio Guadalupe

Johanna Hass

Girma Woldehawariat

Avram J. Holmes

Martine Hoogman

Deborah Janowitz

Tianye Jia

Sungeun Kim

Marieke Klein

Bernd Kraemer

Phil H. Lee

Loes M. Olde Loohuis

Michelle Luciano

Christine Macare

Karen A. Mather

Manuel Mattheisen

Yuri Milaneschi

Kwangsik Nho

Martina Papmeyer

Adaikalavan Ramasamy

Shannon L. Risacher

Roberto Roiz-Santiañez

Emma J. Rose

Alireza Salami

Philipp G. Sämann

机构：

[1] Imaging Genetics Center,Department of Neurology

[2] Institute for Neuroimaging & Informatics,Department of Human Genetics

[3] Keck School of Medicine of the University of Southern California,Department of Psychiatry

[4] Neurogenetics Program,Department of Cognitive Neuroscience

[5] UCLA School of Medicine,Department of Psychiatry

[6] QIMR Berghofer Medical Research Institute,Department of Psychiatry

[7] Brisbane 4006,Department of Computer Science

[8] Australia.,Department of Neuroimaging Sciences

[9] Radboud university medical center,Division of Mental Health and Addiction

[10] Nijmegen 6500 HB,Department of Psychiatry and Biomedical Engineering

[11] The Netherlands.,Interdepartmental Neuroscience Graduate Program

[12] Radboud university medical center,Department of Clinical Science

[13] Nijmegen 6500 HB,Language and Genetics Department

[14] The Netherlands.,Department of Child and Adolescent Psychiatry

[15] Radboud university medical center,Department of Psychology

[16] Nijmegen 6500 HB,Department of Psychiatry

[17] The Netherlands.,Department of Psychiatry and Psychotherapy

[18] Donders Institute for Brain,Department of Psychiatry

[19] Cognition and Behaviour,Department of Biomedicine

[20] Radboud University,Department of Psychiatry

[21] Nijmegen 6500 GL,Division of Psychiatry

[22] The Netherlands.,Department of Medical and Molecular Genetics

[23] MRC-SGDP Centre,Reta Lila Weston Institute and Department of Molecular Neuroscience

[24] Institute of Psychiatry,Department of Psychiatry

[25] Psychology and Neuroscience,Neuropsychiatric Genetics Research Group and Department of Psychiatry

[26] King’s College London,Department of Psychiatry

[27] London SE5 8AF,Department of Neurosciences

[28] UK.,Department of Cognitive Sciences

[29] Laboratory of Human Genetics and Cognitive Functions,Department of Psychology

[30] Institut Pasteur,Nuffield Department of Clinical Neurosciences

[31] Paris 75015,Department of Psychiatry

[32] France.,Department of Neurology and Neurosurgery

[33] Centre Nationale de Recherche Scientifique (CNRS) Unité de Recherche Associée (URA) 2182 Genes,Department of Psychiatric Research and Development

[34] Synapses and Cognition,Department of Medicine

[35] Institut Pasteur,Department of Clinical and Experimental Epilepsy

[36] Paris 75015,Department of Genetics

[37] France.,Division of Medical Genetics, Department of Biomedicine

[38] Université Paris Diderot,Department of Genomics

[39] Sorbonne Paris Cité,Department of Psychiatry and Psychotherapy

[40] Paris 75015,Department of Medical and Molecular Genetics

[41] France.,Division of Genetics, Department of Medicine

[42] German Center for Neurodegenerative Diseases (DZNE) Rostock/Greifswald,Department of Psychiatry

[43] Greifswald 17487,Departments of Cognitive and Clinical Neuropsychology

[44] Germany.,Department of Psychiatry

[45] University Medicine Greifswald,Department of Psychiatry

[46] Greifswald 17489,Department of Pathology and Cell Biology

[47] Germany.,Department of Psychiatry

[48] Brain Center Rudolf Magnus,Department of Statistics & WMG

[49] University Medical Center Utrecht,Department of Psychiatry

[50] Utrecht,Department of Neurology

来源：

Nature | 2015年 / 520卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Genome-wide association studies are used to identify common genetic variants that affect the structure of selected subcortical regions of the human brain; their identification provides insight into the causes of variability in brain development and may help to determine mechanisms of neuropsychiatric dysfunction.

引用

页码：224 / 229

页数：5

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