Common genetic variants influence human subcortical brain structures

被引:0
|
作者
Derrek P. Hibar
Jason L. Stein
Miguel E. Renteria
Alejandro Arias-Vasquez
Sylvane Desrivières
Neda Jahanshad
Roberto Toro
Katharina Wittfeld
Lucija Abramovic
Micael Andersson
Benjamin S. Aribisala
Nicola J. Armstrong
Manon Bernard
Marc M. Bohlken
Marco P. Boks
Janita Bralten
Andrew A. Brown
M. Mallar Chakravarty
Qiang Chen
Christopher R. K. Ching
Gabriel Cuellar-Partida
Anouk den Braber
Sudheer Giddaluru
Aaron L. Goldman
Oliver Grimm
Tulio Guadalupe
Johanna Hass
Girma Woldehawariat
Avram J. Holmes
Martine Hoogman
Deborah Janowitz
Tianye Jia
Sungeun Kim
Marieke Klein
Bernd Kraemer
Phil H. Lee
Loes M. Olde Loohuis
Michelle Luciano
Christine Macare
Karen A. Mather
Manuel Mattheisen
Yuri Milaneschi
Kwangsik Nho
Martina Papmeyer
Adaikalavan Ramasamy
Shannon L. Risacher
Roberto Roiz-Santiañez
Emma J. Rose
Alireza Salami
Philipp G. Sämann
机构
[1] Imaging Genetics Center,Department of Neurology
[2] Institute for Neuroimaging & Informatics,Department of Human Genetics
[3] Keck School of Medicine of the University of Southern California,Department of Psychiatry
[4] Neurogenetics Program,Department of Cognitive Neuroscience
[5] UCLA School of Medicine,Department of Psychiatry
[6] QIMR Berghofer Medical Research Institute,Department of Psychiatry
[7] Brisbane 4006,Department of Computer Science
[8] Australia.,Department of Neuroimaging Sciences
[9] Radboud university medical center,Division of Mental Health and Addiction
[10] Nijmegen 6500 HB,Department of Psychiatry and Biomedical Engineering
[11] The Netherlands.,Interdepartmental Neuroscience Graduate Program
[12] Radboud university medical center,Department of Clinical Science
[13] Nijmegen 6500 HB,Language and Genetics Department
[14] The Netherlands.,Department of Child and Adolescent Psychiatry
[15] Radboud university medical center,Department of Psychology
[16] Nijmegen 6500 HB,Department of Psychiatry
[17] The Netherlands.,Department of Psychiatry and Psychotherapy
[18] Donders Institute for Brain,Department of Psychiatry
[19] Cognition and Behaviour,Department of Biomedicine
[20] Radboud University,Department of Psychiatry
[21] Nijmegen 6500 GL,Division of Psychiatry
[22] The Netherlands.,Department of Medical and Molecular Genetics
[23] MRC-SGDP Centre,Reta Lila Weston Institute and Department of Molecular Neuroscience
[24] Institute of Psychiatry,Department of Psychiatry
[25] Psychology and Neuroscience,Neuropsychiatric Genetics Research Group and Department of Psychiatry
[26] King’s College London,Department of Psychiatry
[27] London SE5 8AF,Department of Neurosciences
[28] UK.,Department of Cognitive Sciences
[29] Laboratory of Human Genetics and Cognitive Functions,Department of Psychology
[30] Institut Pasteur,Nuffield Department of Clinical Neurosciences
[31] Paris 75015,Department of Psychiatry
[32] France.,Department of Neurology and Neurosurgery
[33] Centre Nationale de Recherche Scientifique (CNRS) Unité de Recherche Associée (URA) 2182 Genes,Department of Psychiatric Research and Development
[34] Synapses and Cognition,Department of Medicine
[35] Institut Pasteur,Department of Clinical and Experimental Epilepsy
[36] Paris 75015,Department of Genetics
[37] France.,Division of Medical Genetics, Department of Biomedicine
[38] Université Paris Diderot,Department of Genomics
[39] Sorbonne Paris Cité,Department of Psychiatry and Psychotherapy
[40] Paris 75015,Department of Medical and Molecular Genetics
[41] France.,Division of Genetics, Department of Medicine
[42] German Center for Neurodegenerative Diseases (DZNE) Rostock/Greifswald,Department of Psychiatry
[43] Greifswald 17487,Departments of Cognitive and Clinical Neuropsychology
[44] Germany.,Department of Psychiatry
[45] University Medicine Greifswald,Department of Psychiatry
[46] Greifswald 17489,Department of Pathology and Cell Biology
[47] Germany.,Department of Psychiatry
[48] Brain Center Rudolf Magnus,Department of Statistics & WMG
[49] University Medical Center Utrecht,Department of Psychiatry
[50] Utrecht,Department of Neurology
来源
Nature | 2015年 / 520卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Genome-wide association studies are used to identify common genetic variants that affect the structure of selected subcortical regions of the human brain; their identification provides insight into the causes of variability in brain development and may help to determine mechanisms of neuropsychiatric dysfunction.
引用
收藏
页码:224 / 229
页数:5
相关论文
共 50 条
  • [1] Common genetic variants influence human subcortical brain structures
    Hibar, Derrek P.
    Stein, Jason L.
    Renteria, Miguel E.
    Arias-Vasquez, Alejandro
    Desrivieres, Sylvane
    Jahanshad, Neda
    Toro, Roberto
    Wittfeld, Katharina
    Abramovic, Lucija
    Andersson, Micael
    Aribisala, Benjamin S.
    Armstrong, Nicola J.
    Bernard, Manon
    Bohlken, Marc M.
    Boks, Marco P.
    Bralten, Janita
    Brown, Andrew A.
    Chakravarty, M. Mallar
    Chen, Qiang
    Ching, Christopher R. K.
    Cuellar-Partida, Gabriel
    den Braber, Anouk
    Giddaluru, Sudheer
    Goldman, Aaron L.
    Grimm, Oliver
    Guadalupe, Tulio
    Hass, Johanna
    Woldehawariat, Girma
    Holmes, Avram J.
    Hoogman, Martine
    Janowitz, Deborah
    Jia, Tianye
    Kim, Sungeun
    Klein, Marieke
    Kraemer, Bernd
    Lee, Phil H.
    Loohuis, Loes M. Olde
    Luciano, Michelle
    Macare, Christine
    Mather, Karen A.
    Mattheisen, Manuel
    Milaneschi, Yuri
    Nho, Kwangsik
    Papmeyer, Martina
    Ramasamy, Adaikalavan
    Risacher, Shannon L.
    Roiz-Santianez, Roberto
    Rose, Emma J.
    Salami, Alireza
    Saemann, Philipp G.
    NATURE, 2015, 520 (7546) : 224 - U216
  • [2] Common Genetic Variants Influence Subcortical Brain Volumes: Data from the Philadelphia Neurodevelopmental Cohort
    Satterthwaite, Theodore
    NEUROPSYCHOPHARMACOLOGY, 2014, 39 : S2 - S2
  • [3] Insights Into the Shared Genetic Architecture of Subcortical Brain Structures and Complex Human Traits
    Renteria, Miguel
    BIOLOGICAL PSYCHIATRY, 2021, 89 (09) : S24 - S25
  • [4] Posttraumatic Stress Disorder and Common Genetic Variants Affect Subcortical Brain Volumes in Recent Military Veterans
    Lancaster, Sarah
    Garrett, Melanie
    Haswell, Courtney
    Marx, Christine
    Hauser, Michael
    Ashley-Koch, Allison
    Morey, Rajendra
    NEUROPSYCHOPHARMACOLOGY, 2015, 40 : S455 - S456
  • [5] Distinct Genetic Influences on Cortical and Subcortical Brain Structures
    Wei Wen
    Anbupalam Thalamuthu
    Karen A. Mather
    Wanlin Zhu
    Jiyang Jiang
    Pierre Lafaye de Micheaux
    Margaret J. Wright
    David Ames
    Perminder S. Sachdev
    Scientific Reports, 6
  • [6] Distinct Genetic Influences on Cortical and Subcortical Brain Structures
    Wen, Wei
    Thalamuthu, Anbupalam
    Mather, Karen A.
    Zhu, Wanlin
    Jiang, Jiyang
    de Micheaux, Pierre Lafaye
    Wright, Margaret J.
    Ames, David
    Sachdev, Perminder S.
    SCIENTIFIC REPORTS, 2016, 6
  • [7] Impact of Highly Deleterious Functional Genetic Variants on Subcortical Brain Volume
    Glahn, David
    NEUROPSYCHOPHARMACOLOGY, 2014, 39 : S1 - S2
  • [8] The genetic architecture of human brainstem structures and their involvement in common brain disorders
    Elvsashagen, Torbjorn
    Bahrami, Shahram
    van der Meer, Dennis
    Agartz, Ingrid
    Alnaes, Dag
    Barch, Deanna M.
    Baur-Streubel, Ramona
    Bertolino, Alessandro
    Beyer, Mona K.
    Blasi, Giuseppe
    Borgwardt, Stefan
    Boye, Birgitte
    Buitelaar, Jan
    Boen, Erlend
    Celius, Elisabeth Gulowsen
    Cervenka, Simon
    Conzelmann, Annette
    Coynel, David
    Di Carlo, Pasquale
    Djurovic, Srdjan
    Eisenacher, Sarah
    Espeseth, Thomas
    Fatouros-Bergman, Helena
    Flyckt, Lena
    Franke, Barbara
    Frei, Oleksandr
    Gelao, Barbara
    Harbo, Hanne Flinstad
    Hartman, Catharina A.
    Haberg, Asta
    Heslenfeld, Dirk
    Hoekstra, Pieter J.
    Hogestol, Einar A.
    Jonassen, Rune
    Jonsson, Erik G.
    Kirsch, Peter
    Kloszewska, Iwona
    Lagerberg, Trine Vik
    Landro, Nils Inge
    Le Hellard, Stephanie
    Lesch, Klaus-Peter
    Maglanoc, Luigi A.
    Malt, Ulrik F.
    Mecocci, Patrizia
    Melle, Ingrid
    Meyer-Lindenberg, Andreas
    Moberget, Torgeir
    Nordvik, Jan Egil
    Nyberg, Lars
    O'Connell, Kevin S.
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [9] The genetic architecture of human brainstem structures and their involvement in common brain disorders
    Torbjørn Elvsåshagen
    Shahram Bahrami
    Dennis van der Meer
    Ingrid Agartz
    Dag Alnæs
    Deanna M. Barch
    Ramona Baur-Streubel
    Alessandro Bertolino
    Mona K. Beyer
    Giuseppe Blasi
    Stefan Borgwardt
    Birgitte Boye
    Jan Buitelaar
    Erlend Bøen
    Elisabeth Gulowsen Celius
    Simon Cervenka
    Annette Conzelmann
    David Coynel
    Pasquale Di Carlo
    Srdjan Djurovic
    Sarah Eisenacher
    Thomas Espeseth
    Helena Fatouros-Bergman
    Lena Flyckt
    Barbara Franke
    Oleksandr Frei
    Barbara Gelao
    Hanne Flinstad Harbo
    Catharina A. Hartman
    Asta Håberg
    Dirk Heslenfeld
    Pieter J. Hoekstra
    Einar A. Høgestøl
    Rune Jonassen
    Erik G. Jönsson
    Peter Kirsch
    Iwona Kłoszewska
    Trine Vik Lagerberg
    Nils Inge Landrø
    Stephanie Le Hellard
    Klaus-Peter Lesch
    Luigi A. Maglanoc
    Ulrik F. Malt
    Patrizia Mecocci
    Ingrid Melle
    Andreas Meyer-Lindenberg
    Torgeir Moberget
    Jan Egil Nordvik
    Lars Nyberg
    Kevin S. O’ Connell
    Nature Communications, 11
  • [10] Genetic architecture of subcortical brain regions: common and region-specific genetic contributions
    Renteria, M. E.
    Hansell, N. K.
    Strike, L. T.
    McMahon, K. L.
    de Zubicaray, G. I.
    Hickie, I. B.
    Thompson, P. M.
    Martin, N. G.
    Medland, S. E.
    Wright, M. J.
    GENES BRAIN AND BEHAVIOR, 2014, 13 (08) : 821 - 830