Synthesis of new functionalized 5,5-dimethyl-1-pyrroline 1-oxides and their investigation as spin traps

被引：0
|
作者：
V. A. Golubev
G. V. Shilov
V. D. Sen’
机构：
[1] Russian Academy of Sciences,Institute of Problems of Chemical Physics
来源：
Russian Chemical Bulletin | 2010年 / 59卷
关键词：
nitrones; spin traps; nitroxides; ESR spectroscopy; 5,5-dimethyl-1-pyrroline 1-oxide;
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摘要：
The reactions of 5,5-dimethyl-3-oxo-1-pyrroline 1-oxide (3-oxo-DMPO, 1) with NH2OH and N2H4 afforded oxime (2a) and hydrazone (2b), respectively. The reaction products were studied as spin traps for the short-lived radicals HO·, Ph·, PhCO2·, NC(Me2)C·, and NC(Me2)CO·. The nitroxides generated in the reactions of the above-mentioned short-lived radicals with nitrones 1 and 2a,b were characterized by ESR spectroscopy. Of these nitrones, oxime 2a is the most effective radical trap.
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页码：2081 / 2085
页数：4
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