On the structures of plukenetiones B, D, and E and their relationships to other polycyclic polyprenylated acylphloroglucinols

被引：37
|
作者：
Grossman, RB [1 ]
Jacobs, H
机构：
[1] Univ Kentucky, Dept Chem, Lexington, KY 40506 USA
[2] Univ W Indies, Dept Chem, Kingston 7, Jamaica
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 27期
关键词：
D O I：
10.1016/S0040-4039(00)00832-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Three polycyclic polyprenylated benzoylphloroglucinol natural products, plukenetiones B, D, and E, are shown to be diastereomeric to the related compounds, nemorosone II and sampsonione G. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5165 / 5169
页数：5
相关论文
共 50 条
  • [21] Isolation and Biomimetic Semisynthesis of Hyperzrones A and B, Two Nor-Polycyclic Polyprenylated Acylphloroglucinols with a Characteristic Cyclobutane Moiety, from Hypericum beanii
    Li, Xue-Yan
    Zhang, Lv-Jun
    Yang, Yue-You
    Lu, Wei-Jia
    Ye, Sheng-Tao
    Zhang, Hao
    Kong, Ling-Yi
    Xu, Wen-Jun
    ORGANIC LETTERS, 2024, 26 (50) : 10964 - 10969
  • [22] A New Class of Synthetic Type-B Polycyclic Polyprenylated Acylphloroglucinols (PPAP-B) Overcomes Venetoclax-Resistance in Acute Myeloid Leukemia (AML)
    Kampa, Leonie Elisabeth
    Bleisch, Anton
    Peslalz, Philipp
    Schittenhelm, Marcus Matthias
    Plietker, Bernd
    Kampa-Schittenhelm, Kerstin Maria
    BLOOD, 2023, 142
  • [23] Strategies towards endo-type B polycyclic polyprenylated acylphloroglucinols: total synthesis of regio-hyperibone L and (+)-epi-clusianone
    Wang, Liping
    Wang, Xueying
    Zhang, Guocai
    Fu, Wenwei
    Zhang, Hong
    Zhou, Hua
    Xu, Hongxi
    Zheng, Changwu
    ORGANIC CHEMISTRY FRONTIERS, 2021, 8 (11) : 2525 - 2531
  • [24] First in-class evaluation of type B Polycyclic Polyprenylated Acylphloroglucinols (PPAP) in acute myeloid leukemia (AML) reveals potent antitumor activities
    Moreno, Puig C.
    Izzo, F.
    Kraus, F.
    Peslalz, P.
    Rossberg, P. L.
    Plietker, B.
    Schittenhelm, M. M.
    Kampa-Schittenhelm, K. M.
    ONCOLOGY RESEARCH AND TREATMENT, 2021, 44 : 150 - 151
  • [25] Selective Activation of a TRPC6 Ion Channel Over TRPC3 by Metalated Type-B Polycyclic Polyprenylated Acylphloroglucinols
    Peslalz, Philipp
    Kraus, Frank
    Izzo, Flavia
    Bleisch, Anton
    El Hamdaoui, Yamina
    Schulz, Ina
    Kany, Andreas M.
    Hirsch, Anna K. H.
    Friedland, Kristina
    Plietker, Bernd
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (22) : 15061 - 15072
  • [26] ORGN 464-Synthetic approach to Type B polycyclic polyprenylated acylphloroglucinols (PPAPs): Total synthesis toward Xanthochymol and 7-epi-Clusianone
    Jayasekara, M. P. Suresh
    Grossman, Robert B.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
  • [27] Structure-activity relationship (SAR) studies identify type B polycyclic polyprenylated acylphloroglucinols (PPAPs) with potent antileukemic activity in acute melodic leukemia (AML)
    Kampa, L.
    Hafner, M.
    Ruiba, A.
    Ahrens, A. L.
    Moreno, Puig C.
    Cantero, Sancha M. D. L. A.
    Peslalz, P.
    Bleisch, A.
    Plietker, B.
    Schittenhelm, M.
    Kampa-Schittenhelm, K.
    ONCOLOGY RESEARCH AND TREATMENT, 2022, 45 (SUPPL 2) : 200 - 200
  • [28] CHEMISTRY OF STREPTOVARICINS .8. STRUCTURES OF STREPTOVARICINS A, B, D, E, F, AND G
    RINEHART, KL
    MAHESHWARI, ML
    ANTOSZ, FJ
    MATHUR, HH
    SASAKI, K
    SCHACHT, RJ
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (23) : 6273 - +
  • [29] Identification of turbulent structures of inclined negatively buoyant jets with b e d effects
    Habibi, Shayan
    Azadi, Amin
    Firoozabadi, Bahar
    INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 2023, 208
  • [30] Canadian profile: Alcohol, tobacco, and other drugs - Single,E, Williams,B, McKenzie,D
    Ware, SR
    DRUGS-EDUCATION PREVENTION AND POLICY, 1996, 3 (02) : 219 - 219
12345