Chromoblastomycosis caused by Fonsecaea monophora in Mexico

被引:2
|
作者
Campos-Macias, Pablo [1 ]
Arenas, Roberto [2 ]
Aquino, Caren J. [3 ]
Romero-Navarrete, Marina [4 ]
Martinez-Hernandez, Fernando [5 ]
Martinez-Chavarria, Luary C. [6 ]
Xicohtencatl-Cortes, Juan [7 ]
Hernandez-Castro, Rigoberto [5 ]
机构
[1] Univ Guanajuato, Hosp Aranda Parra, Fac Med, Leon 37000, Spain
[2] Hosp Gen Dr Manuel Gea Gonzalez, Serv Micol, Ciudad De Mexico 14080, Mexico
[3] Ctr Dermatol Sureste Dr Fernando Latapi, Tuxtla Gutierrez 29000, Chiapas, Mexico
[4] Hosp Gen Acapulco, Secretaria Salud, Guerrero 39670, Mexico
[5] Hosp Gen Dr Manuel Gea Gonzalez, Dept Ecol Agentes Patogenos, Ciudad De Mexico 14080, Mexico
[6] Univ Nacl Autonoma Mexico, Dept Patol, Fac Med Vet & Zootecnia, Ciudad De Mexico 04510, Mexico
[7] Hosp Infantil Mexico Dr Federico Gomez, Lab Bacteriol Intestinal, Ciudad de Mexico 06720, Mexico
来源
JOURNAL DE MYCOLOGIE MEDICALE | 2021年 / 31卷 / 02期
关键词
Chromoblastomycosis; F; monophora; Itraconazole; Terbinafine; Fungal infection; IDENTIFICATION; TERBINAFINE; NUBICA; AGENT;
D O I
10.1016/j.mycmed.2021.101114
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Chromoblastomycosis is a chronic subcutaneous fungal infection caused by melanized fungi. It is usually an occupational mycosis affecting people in rural areas in tropical and subtropical regions. We present two cases of chromoblastomycosis in Mexican farmers, characterized by skin verrucous plaques. Direct examination with KOH 10% showed the presence of muriform cells. The fungal isolation was carried out in Sabouraud dextrose agar and molecular identification was achieved by 18S-ITS1-5.8S-ITS2-28S rRNA gene amplification and sequencing. Fonsecaea monophora was identified in both cases. A therapy with itraconazole and terbinafine was used with a partial favorable response. However, patients did not return for medical examination after 4 months. The current status of the patients is unknown. We reported the first two cases of chromoblastomycosis caused by F. monophora in Mexico. (C) 2021 Elsevier Masson SAS. All rights reserved.
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页数:4
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