Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil

被引：13

作者：

Nakasugi, Toru ^{[1
]}

Murakawa, Takushi ^{[1
]}

Shibuya, Koji ^{[2
]}

Morimoto, Masanori ^{[3
]}

机构：

[1] Inabata Koryo Co Ltd, Appl Sci Dept, Chuo Ku, 5-6 Nihonbashi Kobuna Cho, Tokyo 1030024, Japan

[2] Inabata Koryo Co Ltd, Lab Oral Hlth Sci, Chuo Ku, 1-3-21 5F Nihonbashi Horidome Cho, Tokyo 1030012, Japan

[3] Kindai Univ, Sch Agr, Dept Appl Biol Chem, 3327-204 Nakamachi, Nara 6318505, Japan

来源：

JOURNAL OF OLEO SCIENCE | 2017年 / 66卷 / 08期

关键词：

black cumin; thymoquinone; oral deodorant; THYMOQUINONE; EXTRACTION;

D O I：

10.5650/jos.ess17001

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A deodorizing substance in black cumin (Nigella sativa L.), a spice for curry and vegetable foods in Southwest Asia, was examined. The essential oil prepared from the seeds of this plant exhibited strong deodorizing activity against methyl mercaptan, which is a main factor in oral malodor. After purification with silica gel column chromatography, the active substance in black cumin seed oil was identified as thymoquinone. This monoterpenic quinone functions as the main deodorizing substance in this oil against methyl mercaptan. Metabolite analysis suggested that the deodorizing activity may be generated by the addition of a reactive quinone molecule to methyl mercaptan. In the present study, the menthane-type quinone and phenol derivatives exhibited deodorizing activities via this mechanism.

引用

页码：877 / 882

页数：6

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