Fe/Mn Multilayer Nanowires as High-Performance T1-T2 Dual Modal MRI Contrast Agents

被引：11
|
作者：
Cao, Xiaoming [1 ]
Gu, Liyuan [2 ]
Hu, Shike [2 ]
Mukhtar, Aiman [1 ]
Wu, Kaiming [1 ]
机构：
[1] Wuhan Univ Sci & Technol, State Key Lab Refractories & Met, Hubei Prov Key Lab Syst Sci Met Proc, Collaborat Innovat Ctr Adv Steels,Int Res Inst St, Wuhan 430081, Peoples R China
[2] Hubei Univ Sci & Technol, Res & Dev Ctr Nonpowered Nucl Technol, Xianning 437000, Peoples R China
来源：
MATERIALS | 2021年 / 14卷 / 09期
关键词：
dual modal; MRI; CAs; nanowire; relaxation; IRON-OXIDE NANOPARTICLES; T-1; RELAXIVITY; DESIGN;
D O I：
10.3390/ma14092238
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A lot of nanomaterials are using T-1-T-2 dual mode magnetic resonance (MR) contrast agents (CAs), but multilayer nanowire (NW) with iron (Fe) and manganese (Mn) as T-1-T-2 dual modal CAs has not been reported yet. Herein, we synthesized a Fe/Mn multilayer NW with an adjustable Fe layer, as T-1-T-2 dual-mode CAs. The relaxation performance of Fe/Mn multilayer NW was studied at 1.5 T. Results show that, when the length of the Fe layer is about 10 nm and the Mn is about 5 nm, the r(1) value (21.8 mM(-1)s(-1)) and r(2) value (74.8 mM(-1)s(-1)) of the Fe/Mn multilayer NW are higher than that of Mn NW (3.7 mM(-1)s(-1)) and Fe NW (59.3 mM(-1)s(-1)), respectively. We predict that our Fe/Mn multilayer NW could be used as T-1-T-2 dual mode MRI CAs in the near future.
引用
收藏
页数：15
相关论文
共 50 条
  • [21] Catechin tuned magnetism of Gd-doped orthovanadate through morphology as T1-T2 MRI contrast agents
    Tamilmani Vairapperumal
    Ariya Saraswathy
    Jayasree S. Ramapurath
    Sreeram Kalarical Janardhanan
    Nair Balachandran Unni
    Scientific Reports, 6
  • [22] Catechin tuned magnetism of Gd-doped orthovanadate through morphology as T1-T2 MRI contrast agents
    Vairapperumal, Tamilmani
    Saraswathy, Ariya
    Ramapurath, Jayasree S.
    Sreeram, Kalarical Janardhanan
    Unni, Nair Balachandran
    SCIENTIFIC REPORTS, 2016, 6
  • [23] Core-Shell Structurized Fe3O4@C@MnO2 Nanoparticles as pH Responsive T1-T2* Dual-Modal Contrast Agents for Tumor Diagnosis
    Duan, Beichen
    Wang, Dongdong
    Wu, Huihui
    Xu, Pengping
    Jiang, Peng
    Xia, Guoliang
    Liu, Zhenbang
    Wang, Haibao
    Guo, Zhen
    Chen, Qianwang
    ACS BIOMATERIALS SCIENCE & ENGINEERING, 2018, 4 (08): : 3047 - 3054
  • [24] A "Dual-Key-and-Lock" MRI Contrast Agent with T1-T2 Switchable Function for Accurate Diagnosis of Tumors
    Lu, Zhongzhong
    Yan, Jincong
    Xu, Mingsheng
    Liu, Jihuan
    Zeng, Jianxian
    Ren, Yuxin
    Sun, Lina
    Zhang, Ye
    Cao, Yi
    Pei, Renjun
    NANO LETTERS, 2024, 24 (30) : 9406 - 9414
  • [25] NMR investigation of functionalized magnetic nanoparticles Fe3O4 as T1-T2 contrast agents
    Kenouche, S.
    Larionova, J.
    Bezzi, N.
    Guari, Y.
    Bertin, N.
    Zanca, M.
    Lartigue, L.
    Cieslak, M.
    Godin, C.
    Morrot, G.
    Goze-Bac, C.
    POWDER TECHNOLOGY, 2014, 255 : 60 - 65
  • [26] A Protein-Corona-Free T1-T2 Dual-Modal Contrast Agent for Accurate Imaging of Lymphatic Tumor Metastasis
    Zhou, Zijian
    Liu, Hanyu
    Chi, Xiaoqin
    Chen, Jiahe
    Wang, Lirong
    Sun, Chengjie
    Chen, Zhong
    Gao, Jinhao
    ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (51) : 28286 - 28293
  • [27] T1-T2 dual-modal MRI of brain gliomas using PEGylated Gd-doped iron oxide nanoparticles
    Xiao, Ning
    Gu, Wei
    Wang, Hao
    Deng, Yunlong
    Shi, Xin
    Ye, Ling
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2014, 417 : 159 - 165
  • [28] Janus nanoparticles for contrast enhancement of T1-T2 dual mode magnetic resonance imaging
    Deka, Kashmiri
    Guleria, Anupam
    Kumar, Dinesh
    Biswas, Jayeeta
    Lodha, Saurabh
    Kaushik, Som Datta
    Choudhary, Saynaz A.
    Dasgupta, Suman
    Deb, Pritam
    DALTON TRANSACTIONS, 2019, 48 (03) : 1075 - 1083
  • [29] Shape programmable T1-T2 dual-mode MRI nanoprobes for cancer theranostics
    Liu, Menghan
    Yuan, Jia
    Wang, Gongzheng
    Ni, Nengyi
    Lv, Qian
    Liu, Shuangqing
    Gong, Yufang
    Zhao, Xinya
    Wang, Ximing
    Sun, Xiao
    NANOSCALE, 2023, 15 (10) : 4694 - 4724
  • [30] Development of macrocyclic Fe(III) T1 MRI contrast agents
    Asik, Didar
    Snyder, Eric
    Spernyak, Joseph
    Morrow, Janet
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
12345