A bifacial topological template exhibiting metal-binding sites and thioalkane chains has been incorporated into self-assembled monolayers and immobilised on gold surfaces: These systems allow for the detection of external ligands by SPR spectroscopy representing a first step in developing biosensors based on the TASP (Template Assembled Synthetic Proteins) concept.
机构:
Univ Wisconsin, Dept Biomed Engn Pharmacol & Mat Sci & Engn, Madison, WI 53706 USAUniv Wisconsin, Dept Biomed Engn Pharmacol & Mat Sci & Engn, Madison, WI 53706 USA
Murphy, William L.
Collier, Joel H.
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机构:
Univ Chicago, Dept Surg, Chicago, IL 60637 USA
Univ Chicago, Comm Mol Med, Div Res, Chicago, IL 60637 USAUniv Wisconsin, Dept Biomed Engn Pharmacol & Mat Sci & Engn, Madison, WI 53706 USA