Inhibition of ABCB1 overcomes cancer stem cell-like properties and acquired resistance to MET inhibitor in non-small cell lung cancer

被引：0
|
作者：
Sugano, Teppei [1 ]
Seike, Masahiro [1 ]
Noro, Rintaro [1 ]
Soeno, Chie [1 ]
Nakamichi, Shinji [1 ]
Nishijima, Nobuhiko [1 ]
Matsumoto, Masaru [1 ]
Takeuchi, Susumu [1 ]
Miyanaga, Akihiko [1 ]
Kubota, Kaoru [1 ]
Gemma, Akihiko [1 ]
机构：
[1] Nippon Med Sch, Grad Sch Med, Dept Pulm Med & Oncol, Tokyo 113, Japan
来源：
CANCER RESEARCH | 2015年 / 75卷
关键词：
D O I：
10.1158/1538-7445.AM2015-756
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
756
引用
收藏
页数：2
相关论文
共 50 条
  • [21] MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling
    Meng Chen
    Li-Xin Sun
    Long Yu
    Jun Liu
    Li-Chao Sun
    Zhi-Hua Yang
    Xiong Shu
    Yu-Liang Ran
    Cell Death Discovery, 7
  • [22] A MET Inhibitor in the Treatment of Metastatic Non-Small Cell Lung Cancer with MET Amplification
    Zhang, Tongtong
    Li, Junling
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S236 - S236
  • [23] CANCER STEM CELL-LIKE POPULATION FROM NON-SMALL CELL LUNG CANCER IS PREFERENTIALLY SUPPRESSED BY EGFR-TKIS
    Zhou, Qinghua
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S465 - S465
  • [24] Modulation of the Sonic Hedgehog Signaling Pathway in Non-small Cell Lung Cancer Targets Stem Cell-like Cancer Cells
    Csiki, I.
    Martyn, C.
    Freeman, M.
    Carbone, D.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 78 (03): : S112 - S113
  • [25] Cancer stem cell-like population from non-small cell lung cancer is preferentially suppressed by EGFR-TKIs.
    Yang, Fan
    You, Jiacong
    Li, Yang
    Liao, Jiayu
    Zhou, Qinghua
    CANCER RESEARCH, 2013, 73 (08)
  • [26] Increased expression of ABCB1 could be associated with osimertinib resistance in non-small cell lung cancer cell line PC9 cell
    Nomizo, Takashi
    Ozasa, Hiroaki
    Tsuji, Takahiro
    Yasuda, Yuto
    Funazo, Tomoko
    Yoshida, Hironori
    Sakamori, Yuichi
    Nagai, Hiroki
    Kim, Young Hak
    CANCER RESEARCH, 2017, 77
  • [27] The ALK inhibitor LDK378 overcomes crizotinib resistance in non-small cell lung cancer
    Friboulet, Luc
    Li, Nanxin
    Katayama, Ryohei
    Lee, Christian C.
    Gainor, Justin F.
    Crystal, Adam S.
    Michellys, Pierre-Yves
    Awad, Mark M.
    Yanagitani, Noriko
    Kim, Sungjoon
    Pferdekamper, AnneMarie
    Li, Jie
    Kasibhatla, Shailaja
    Sun, Frank
    Sun, Xiuying
    Hua, Su
    McNamara, Peter
    Mahmood, Sidra
    Lockerman, Elizabeth L.
    Fujita, Naoya
    Nishio, Makoto
    Harris, Jennifer L.
    Shaw, Alice T.
    Engelman, Jeffrey A.
    CANCER RESEARCH, 2014, 74 (19)
  • [28] Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non-Small Cell Lung Cancer
    Sang, Jim
    Acquaviva, Jaime
    Friedland, Julie C.
    Smith, Donald L.
    Sequeira, Manuel
    Zhang, Chaohua
    Jiang, Qin
    Xue, Liquan
    Lovly, Christine M.
    Jimenez, John-Paul
    Shaw, Alice T.
    Doebele, Robert C.
    He, Suqin
    Bates, Richard C.
    Camidge, D. Ross
    Morris, Stephan W.
    El-Hariry, Iman
    Proia, David A.
    CANCER DISCOVERY, 2013, 3 (04) : 430 - 443
  • [29] Fingolimod augments Pemetrexed killing of non-small cell lung cancer and overcomes resistance to ERBB inhibition
    Booth, Laurence
    Roberts, Jane L.
    Spiegel, Sarah
    Poklepovic, Andrew
    Dent, Paul
    CANCER BIOLOGY & THERAPY, 2019, 20 (05) : 597 - 607
  • [30] Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line
    Douglas D. Fang
    Joan Cao
    Jitesh P. Jani
    Konstantinos Tsaparikos
    Alessandra Blasina
    Jill Kornmann
    Maruja E. Lira
    Jianying Wang
    Zuzana Jirout
    Justin Bingham
    Zhou Zhu
    Yin Gu
    Gerrit Los
    Zdenek Hostomsky
    Todd VanArsdale
    Frontiers of Medicine, 2013, 7 : 462 - 476
12345