Vogt-Koyanagi-Harada syndrome presenting with bilateral optic disc swelling and leptomeningeal enhancement

被引:3
|
作者
Le, Thanh-Thao Adriana [1 ]
Simon, Sumu [2 ]
Gilhotra, Jagjit [3 ]
Hissaria, Pravin [1 ,4 ]
机构
[1] Royal Adelaide Hosp, Clin Immunol & Allergy, Adelaide, SA, Australia
[2] Royal Adelaide Hosp, Ophthalmol, Adelaide, SA, Australia
[3] Royal Adelaide Hosp, South Australian Inst Ophthalmol, Adelaide, SA, Australia
[4] SA Pathology, Immunol, Adelaide, SA, Australia
关键词
ophthalmology; neuroopthalmology; neuroimaging; immunology;
D O I
10.1136/bcr-2019-229719
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vogt-Koynagi-Harada (VKH) disease is a clinical syndrome with classical ocular and extraocular findings that is not uncommonly described in Asian, Middle-Eastern and South American populations. We describe a case of VKH in an elderly Polish-Australian distinguished by prominent bilateral disc swelling rather than uveitis and marked leptomeningeal enhancement on MRI which led to extensive investigation including brain biopsy. Both disc oedema and MRI abnormalities improved dramatically with systemic steroid therapy. VKH disease is an important differential to consider in older patients with an uveo-meningeal picture and atypical eye findings where other causes have been excluded.
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页数:4
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