Myofibroblast YAP/TAZ is dispensable for liver fibrosis in mice

被引：7
|
作者：
Xu, Liran [1 ]
Wettschureck, Nina [2 ,3 ]
Bai, Yongping [4 ]
Yuan, Zuyi [5 ]
Wang, Shengpeng [1 ,2 ,5 ]
机构：
[1] Xi An Jiao Tong Univ, Hlth Sci Ctr, Key Lab Environm & Genes Related Dis, Cardiovasc Res Ctr,Sch Basic Med Sci, Xian, Peoples R China
[2] Max Planck Inst Heart & Lung Res, Dept Pharmacol, Bad Nauheim, Germany
[3] Goethe Univ, Ctr Mol Med, Frankfurt, Germany
[4] Cent South Univ, Xiangya Hosp, Dept Geriatr Med, Changsha, Peoples R China
[5] Xi An Jiao Tong Univ, Dept Cardiol, Affiliated Hosp 1, West Yanta Rd 277, Xian 710061, Peoples R China
来源：
JOURNAL OF HEPATOLOGY | 2021年 / 75卷 / 01期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/j.jhep.2021.02.026
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：238 / 241
页数：5
相关论文
共 50 条
  • [21] AMPK stimulation inhibits YAP/TAZ signaling to ameliorate hepatic fibrosis
    Mahbubul H. Shihan
    Sachin Sharma
    Carson Cable
    Vijaya Prathigudupu
    Alina Chen
    Aras N. Mattis
    Jennifer Y. Chen
    Scientific Reports, 14
  • [22] Signaling in fibrosis: TGF-beta, wNT, and YAP/TAZ converge
    Piersma, Bram
    Bank, Ruud A.
    Boersema, Miriam
    FRONTIERS IN MEDICINE, 2015, 2
  • [23] Fibroblast Yap/Taz Signaling in Extracellular Matrix Homeostasis and Tissue Fibrosis
    Chu, Cong-Qiu
    Quan, Taihao
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (12)
  • [24] Dysregulated ATX-LPA and YAP/TAZ signaling in dystrophic Sgcd-/- mice with early fibrosis and inflammation
    Gutierrez-Rojas, Cristian
    Cordova-Casanova, Adriana
    Faundez-Contreras, Jennifer
    Cruz-Soca, Meilyn
    Gallardo, Felipe S.
    Bock-Pereda, Alexia
    Casar, Juan Carlos
    Barton, Elisabeth R.
    Brandan, Enrique
    SKELETAL MUSCLE, 2025, 15 (01):
  • [25] Yap1/Taz are essential for the liver development in zebrafish
    Yi, Xiaogui
    Yu, Jia
    Ma, Chao
    Li, Li
    Luo, Lingfei
    Li, Hongtao
    Ruan, Hua
    Huang, Honghui
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 503 (01) : 131 - 137
  • [26] BETting on YAP–TAZ
    Ulrike Harjes
    Nature Reviews Cancer, 2018, 18 : 663 - 663
  • [27] Jiawei Qi Gong Wan improves liver fibrosis and inflammation in PCOS mice via the Akt2-FoxO1 and YAP/TAZ signaling pathways
    Li, Jie
    Zheng, Ruqun
    Shen, Yingyan
    Zhuo, Yuxuan
    Lu, Lingjing
    Song, Jinlong
    Li, Jing
    Lai, Maohua
    Zhu, He
    Hu, Min
    Ma, Hongxia
    Li, Juan
    PHYTOMEDICINE, 2025, 136
  • [28] ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation
    Zhang, Kun
    Chang, Yanan
    Shi, Zhemin
    Han, Xiaohui
    Han, Yawei
    Yao, Qingbin
    Hu, Zhimei
    Cui, Hongmei
    Zheng, Lina
    Han, Tao
    Hong, Wei
    SCIENTIFIC REPORTS, 2016, 6
  • [29] ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation
    Kun Zhang
    Yanan Chang
    Zhemin Shi
    Xiaohui Han
    Yawei Han
    Qingbin Yao
    Zhimei Hu
    Hongmei Cui
    Lina Zheng
    Tao Han
    Wei Hong
    Scientific Reports, 6
  • [30] Myofibroblast expression and apoptosis in experimental liver fibrosis
    Tsamandas, A
    Kalogeropoulou, C
    Ravazoula, P
    Tepetes, K
    Petsas, T
    Karavias, D
    Bonikos, D
    MODERN PATHOLOGY, 2002, 15 (01) : 295A - 295A
12345