Sperm selection by swim-up in terms of deoxyribonucleic acid fragmentation as measured by the sperm chromatin dispersion test is altered in heavy smokers

被引：25
|
作者：
Viloria, Thamara
Garrido, Nicolas
Fernandez, Jose Luis
Remohi, Jose
Pellicer, Antonio
Meseguer, Marcos
机构：
[1] Instituto Valenciano de Infertilidad, Valencia, Universidad de Valencia, Valencia
[2] Sección de Genetica y Unidad de Investigación, Hospital Teresa Herrera, Complejo Hospitalario Universitario Juan Canalejo, A Coruña
[3] Department of Obstetrics and Gynaecology, Hospital Dr. Peset, Valencia
来源：
FERTILITY AND STERILITY | 2007年 / 88卷 / 02期
关键词：
D O I：
10.1016/j.fertnstert.2006.11.135
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Toxic habits and their relationship with male factor infertility have been a matter of investigation in recent years, and smoking is one of the most common lifestyle toxic exposures to harmful substances. The analysis of sperm deoxyribonucleic acid fragmentation after capacitation detected a detrimental effect produced by tobacco, and this deleterious effect alters the sperm swim-up selection process in smokers, although the molecular and cellular basis of this phenomenon remain to be elucidated. (Fertil Steril((R)) 2007;88:523-5. (c) 2007 by American Society for Reproductive Medicine.).
引用
收藏
页码：523 / 525
页数：3
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