Sperm selection by swim-up in terms of deoxyribonucleic acid fragmentation as measured by the sperm chromatin dispersion test is altered in heavy smokers

被引：25

作者：

Viloria, Thamara

Garrido, Nicolas

Fernandez, Jose Luis

Remohi, Jose

Pellicer, Antonio

Meseguer, Marcos

机构：

[1] Instituto Valenciano de Infertilidad, Valencia, Universidad de Valencia, Valencia

[2] Sección de Genetica y Unidad de Investigación, Hospital Teresa Herrera, Complejo Hospitalario Universitario Juan Canalejo, A Coruña

[3] Department of Obstetrics and Gynaecology, Hospital Dr. Peset, Valencia

来源：

FERTILITY AND STERILITY | 2007年 / 88卷 / 02期

关键词：

D O I：

10.1016/j.fertnstert.2006.11.135

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Toxic habits and their relationship with male factor infertility have been a matter of investigation in recent years, and smoking is one of the most common lifestyle toxic exposures to harmful substances. The analysis of sperm deoxyribonucleic acid fragmentation after capacitation detected a detrimental effect produced by tobacco, and this deleterious effect alters the sperm swim-up selection process in smokers, although the molecular and cellular basis of this phenomenon remain to be elucidated. (Fertil Steril((R)) 2007;88:523-5. (c) 2007 by American Society for Reproductive Medicine.).

引用

页码：523 / 525

页数：3

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