Serologic Response to Hepatitis B Vaccination in HIV-Infected Patients with Isolated Positivity for Antibodies to Hepatitis B Core Antigen

被引：25

作者：

Chakvetadze, Catherine ^{[1
]}

Bani-Sadr, Firouze ^{[1
]}

Le Pendeven, Catherine ^{[2
]}

Lescure, Francois-Xavier ^{[1
]}

Fontaine, Camille ^{[1
]}

Galperine, Tatiana ^{[1
]}

Slama, Laurence ^{[1
]}

Bonnard, Philippe ^{[1
]}

Mariot, Philippe ^{[1
]}

Soussan, Patrick ^{[2
]}

Pialoux, Gilles ^{[1
]}

机构：

[1] Hop Tenon, Serv Malad Infect & Trop, F-75970 Paris 20, France

[2] Hop Tenon, Virol Lab, F-75970 Paris 20, France

来源：

CLINICAL INFECTIOUS DISEASES | 2010年 / 50卷 / 08期

关键词：

A VACCINE; VIRUS; ADULTS; HBS; INJECTIONS; EFFICACY; NUMBER;

D O I：

10.1086/651422

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We assessed the safety and immunogenicity of hepatitis B vaccination among 40 human immunodeficiency virus-infected patients with isolated positivity for antibodies to hepatitis B core antigen. No baseline factors were found to be predictive of an anamnestic response, which occurred in 32.5% of the patients. The overall response rate among patients without an anamnestic response was 74.0% after 3-6 vaccine doses.

引用

页码：1184 / 1186

页数：3

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