Synthesis and evaluation of new 1,3,4-oxadiazoles and 1,3,4-oxadiazole-2-thione derivatives of nalidixic acid as potential antibacterial and antifungal agents

被引：0
|
作者：
Grover, G [1 ]
Kini, SG [1 ]
机构：
[1] Coll Pharmaceut Sci, Dept Pharmaceut Chem, Manipal 576119, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2003年 / 12卷 / 03期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series. of new. nalidixic acid derivatives having 1,3,4-oxadiazole and 1,3,4-oxadiazole-thione, were synthesized carrying the biodynamic heterocyclic systems at position-3 with a view to secure biheterocycles of enhanced biological activities.
引用
收藏
页码：289 / 290
页数：2
相关论文
共 50 条
  • [1] SYNTHESIS OF NEW 1,3,4-OXADIAZOLES AS ANTIBACTERIAL AND ANTIFUNGAL AGENTS
    Revanasiddappa, B. C.
    Varghese, Saira Susan
    Kalsi, Jasmine
    Jisha, M. S.
    Jose, Neethu
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 24 (01) : 93 - 96
  • [2] Synthesis and Antiplatelet Potential Evaluation of 1,3,4-Oxadiazoles Derivatives
    Ramzan, Ayesha
    Nazeer, Areesha
    Irfan, Ahmad
    Al-Sehemi, Abdullah G.
    Verpoort, Francis
    Khatak, Zafar A.
    Ahmad, Aftab
    Munawar, Munawar A.
    Khan, Misbahul A.
    Basra, Muhammad Asim Raza
    ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS, 2019, 233 (12): : 1741 - 1759
  • [3] Synthesis and biological evaluation of 1,2,4-triazole-3-thione and 1,3,4-oxadiazole-2-thione as antimycobacterial agents
    Sonawane, Amol D.
    Rode, Navnath D.
    Nawale, Laxman
    Joshi, Rohini R.
    Joshi, Ramesh A.
    Likhite, Anjali P.
    Sarkar, Dhiman
    CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 90 (02) : 200 - 209
  • [4] Synthesis of Novel Nalidixic Acid-Based 1,3,4-Thiadiazole and 1,3,4-Oxadiazole Derivatives as Potent Antibacterial Agents
    Aggarwal, Nisha
    Kumar, Rajesh
    Dureja, Prem
    Khurana, Jitender Mohan
    CHEMICAL BIOLOGY & DRUG DESIGN, 2012, 79 (04) : 384 - 397
  • [5] Synthesis and antifungal activity of some new 1,3,4-oxadiazoles
    Bakht, MA
    Islam, M
    Siddiqui, AA
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2006, 15 (03) : 297 - 298
  • [6] Synthesis and QSAR studies of thiosemicarbazides, 1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles derivatives as potential antibacterial agents
    Desai, N. C.
    Bhavsar, A. M.
    Shah, M. D.
    Saxena, Anil K.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2008, 47 (04): : 579 - 585
  • [7] Synthesis, thymidine phosphorylase inhibitory and computational study of novel 1,3,4-oxadiazole-2-thione derivatives as potential anticancer agents
    Bajaj, Shalini
    Roy, Partha Pratim
    Singh, Jagadish
    COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 76 : 151 - 160
  • [8] SYNTHESIS OF ORGANOSILICON DERIVATIVES OF 1,3,4-OXADIAZOLES AND 1,3,4-THIADIAZOLE
    GOLDIN, GS
    MAKSAKOVA, MV
    PODDUBNYI, VG
    KOLTSOVA, AN
    ZHURNAL OBSHCHEI KHIMII, 1975, 45 (12): : 2661 - 2665
  • [9] Synthesis and biological evaluation of 1,3,4-oxadiazole fused pyridine derivatives as antibacterial and antifungal agents
    Subhashini, N. J. P.
    Bhadraiah, B.
    Janaki, P.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (03) : 550 - 553
  • [10] In vitro antitumor and antiviral activities of new benzothiazole and 1,3,4-oxadiazole-2-thione derivatives
    Akhtar, Tashfeen
    Hameed, Shahid
    Al-Masoudi, Najim A.
    Loddo, Roberta
    La Colla, Paolo
    ACTA PHARMACEUTICA, 2008, 58 (02) : 135 - 149
12345