Synthesis and antifungal activity of some new 1,3,4-oxadiazoles

被引：0
|
作者：
Bakht, MA [1 ]
Islam, M [1 ]
Siddiqui, AA [1 ]
机构：
[1] Hamdard Univ, Fac Pharm, Dept Pharmaceut Chem, New Delhi 110062, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 15卷 / 03期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 5-{2-[(p-substituted phenyl) amino] ethyl}-N-(substituted phenyl)-1,3,4-oxadiazol-2-amines (3a-h) was synthesized by reacting 3-(4-substituted anilino) propionic acid hydrazide with substituted phenyl isothiocyanates. The final compounds, 3a-h were structurally confirmed on the basis of their spectral and analytical data. The compounds showed promising results as antifungal agents compared with standard drug at similar concentration.
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页码：297 / 298
页数：2
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