The co-crystal of two GRAS substances: (citric acid)•(nicotinamide). Formation of four hydrogen bonding heterosynthons in one co-crystal

被引：33
|
作者：
Lemmerer, Andreas [1 ]
Bernstein, Joel [1 ]
机构：
[1] Ben Gurion Univ Negev, Dept Chem, IL-84105 Beer Sheva, Israel
来源：
CRYSTENGCOMM | 2010年 / 12卷 / 07期
基金：
新加坡国家研究基金会; 美国国家科学基金会;
关键词：
ACTIVE PHARMACEUTICAL INGREDIENTS; CARBAMAZEPINE-NICOTINAMIDE COCRYSTALS; MOLECULAR-COMPLEXES; CARBOXYLIC-ACIDS; ORGANIC-ACIDS; CITRIC-ACID; PHASES; CRYSTALLIZATION; CAFFEINE; KINETICS;
D O I：
10.1039/b927422g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The co-crystal between the GRAS molecules citric acid and nicotinamide contains four different heteromeric interactions, whose known frequency in other nicotinamide co-crystals further illustrates their robustness.
引用
收藏
页码：2029 / 2033
页数：5
相关论文
共 50 条
  • [21] Spectroscopic characterization of single co-crystal of mefenamic acid and nicotinamide using supercritical CO2
    Vaksler, Ye A.
    Benedis, D.
    Dyshin, A. A.
    Oparin, R. D.
    Correia, N. T.
    Capet, F.
    Shishkina, S., V
    Kiselev, M. G.
    Idrissi, A.
    JOURNAL OF MOLECULAR LIQUIDS, 2021, 334
  • [22] Lack of Co-crystal Formation with Cyclotriphosphazenes: A Cautionary Tale
    Wahl, Helene
    Haynes, Delia A.
    le Roex, Tanya
    SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE, 2016, 69 : 35 - +
  • [23] Supramolecular recognition in solution towards co-crystal formation
    Edkins, K.
    Shen, Y.
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2022, 78 : E214 - E214
  • [24] Scalability of Pharmaceutical Co-Crystal Formation by Mechanochemistry in Batch
    Bodach, Alexander
    Portet, Anais
    Winkelmann, Frederik
    Herrmann, Bastian
    Gallou, Fabrice
    Ponnusamy, Ettigounger
    Virieux, David
    Colacino, Evelina
    Felderhoff, Michael
    CHEMSUSCHEM, 2024, 17 (06)
  • [25] A 1:2 co-crystal of isonicotinamide and propionic acid
    Oswald, IDH
    Motherwell, WDS
    Parsons, S
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2004, 60 : O2380 - O2383
  • [26] Evolution of the hydrogen-bonding motif in the melamine-cyanuric acid co-crystal: a topological study
    Petelski, Andre N.
    Peruchena, Nelida M.
    Sosa, Gladis L.
    JOURNAL OF MOLECULAR MODELING, 2016, 22 (09)
  • [27] Simvastatin-nicotinamide co-crystal: design, preparation and preliminary characterization
    Sopyan, Iyan
    Fudholi, Achmad
    Muchtaridi, Muchtaridi
    Sari, Ika Puspita
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2017, 16 (02) : 297 - 303
  • [28] The structure of the melamine-cyanuric acid co-crystal
    Prior, Timothy J.
    Armstrong, Jennifer A.
    Benoit, David M.
    Marshall, Kayleigh L.
    CRYSTENGCOMM, 2013, 15 (29): : 5838 - 5843
  • [29] Structure and properties of a co-crystal of malonic acid with acetamide
    A. Yu. Tsyplenkova
    O. V. Kol’tsova
    N. N. Lobanov
    M. A. Ershov
    Yu. Yu. Pyl’chikova
    Journal of Structural Chemistry, 2016, 57 : 1691 - 1693
  • [30] STRUCTURE AND PROPERTIES OF A CO-CRYSTAL OF MALONIC ACID WITH ACETAMIDE
    Tsyplenkova, A. Yu.
    Kol'tsova, O. V.
    Lobanov, N. N.
    Ershov, M. A.
    Pyl'chikova, Yu. Yu.
    JOURNAL OF STRUCTURAL CHEMISTRY, 2016, 57 (08) : 1691 - 1693
12345