Lewis acid-catalyzed redox-neutral amination of 2-(3-pyrroline-1-yl)benzaldehydes via intramolecular [1,5]-hydride shift/isomerization reaction

被引：9
|
作者：
Jiang, Chun-Huan [1 ,2 ]
Lei, Xiantao [1 ,2 ]
Zhen, Le [1 ,2 ]
Du, Hong-Jin [1 ,2 ]
Wen, Xiaoan [1 ,2 ]
Xu, Qing-Long [1 ,2 ]
Sun, Hongbin [1 ,2 ]
机构：
[1] China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Jiangsu, Peoples R China
[2] China Pharmaceut Univ, Jiangsu Key Lab Drug Discovery Metab Dis, Nanjing 210009, Jiangsu, Peoples R China
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 10卷
基金：
中国国家自然科学基金;
关键词：
catalysis; C-H activation; hydride-shift; Lewis acid; redox reaction; H BOND FUNCTIONALIZATION; CYCLIC AMINALS; ACTIVATION; CHEMISTRY; ARYLATION; PYRROLES; COMPLEX;
D O I：
10.3762/bjoc.10.306
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Lewis acid-catalyzed redox-neutral amination of 2-(3-pyrroline-1-yl) benzaldehydes via intramolcular [1,5]-hydride shift/isomerization reaction has been realized, using the inherent reducing power of 3-pyrrolines. A series of N-arylpyrrole containing amines are obtained in high yields.
引用
收藏
页码：2892 / 2896
页数：5
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