Pandemic potential of avian influenza A (H7N9) viruses

被引：99
|
作者：
Watanabe, Tokiko [1 ,2 ,3 ]
Watanabe, Shinji [2 ,4 ]
Maher, Eileen A. [1 ]
Neumann, Gabriele [1 ]
Kawaoka, Yoshihiro [1 ,2 ,3 ,5 ]
机构：
[1] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI 53711 USA
[2] Japan Sci & Technol Agcy, ERATO Infect Induced Host Responses Project, Kawaguchi, Saitama 3320012, Japan
[3] Univ Tokyo, Inst Med Sci, Div Virol, Dept Microbiol & Immunol, Tokyo 1088639, Japan
[4] Miyazaki Univ, Lab Vet Microbiol, Dept Vet Sci, Miyazaki 8892192, Japan
[5] Univ Tokyo, Dept Special Pathogens, Int Res Ctr Infect Dis, Inst Med Sci, Tokyo 1088639, Japan
来源：
TRENDS IN MICROBIOLOGY | 2014年 / 22卷 / 11期
基金：
日本科学技术振兴机构;
关键词：
avian influenza H7N9 viruses; transmission; pandemic potential; AMINO-ACID SUBSTITUTIONS; HOST-RANGE DETERMINANTS; TO-PERSON TRANSMISSION; A(H7N9) VIRUS; HUMAN INFECTION; RECEPTOR-BINDING; CLINICAL FINDINGS; JIANGSU PROVINCE; MOLECULAR-BASIS; CHINA;
D O I：
10.1016/j.tim.2014.08.008
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Avian influenza viruses rarely infect humans, but the recently emerged avian H7N9 influenza viruses have caused sporadic infections in humans in China, resulting in 440 confirmed cases with 122 fatalities as of 16 May 2014. In addition, epidemiologic surveys suggest that there have been asymptomatic or mild human infections with H7N9 viruses. These viruses replicate efficiently in mammals, show limited transmissibility in ferrets and guinea pigs, and possess mammalian-adapting amino acid changes that likely contribute to their ability to infect mammals. In this review, we summarize the characteristic features of the novel H7N9 viruses and assess their pandemic potential.
引用
收藏
页码：623 / 631
页数：9
相关论文
共 50 条
  • [1] The pandemic potential of avian influenza A(H7N9) virus: a review
    Tanner, W. D.
    Toth, D. J. A.
    Gundlapalli, A. V.
    [J]. EPIDEMIOLOGY AND INFECTION, 2015, 143 (16): : 3359 - 3374
  • [2] Potential Pandemic of H7N9 Avian Influenza A Virus in Human
    Pu, Zhiqing
    Xiang, Dan
    Li, Xiaobing
    Luo, Tingting
    Shen, Xuejuan
    Murphy, Robert W.
    Liao, Ming
    Shen, Yongyi
    [J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2018, 8
  • [3] Avian influenza H7N9 viruses: a rare second warning
    Kanta Subbarao
    [J]. Cell Research, 2018, 28 : 1 - 2
  • [4] Genesis of avian-origin H7N9 influenza A viruses
    Van Ranst, Marc
    Lemey, Philippe
    [J]. LANCET, 2013, 381 (9881): : 1883 - 1885
  • [5] Avian influenza H7N9 viruses: a rare second warning
    Subbarao, Kanta
    [J]. CELL RESEARCH, 2018, 28 (01) : 1 - 2
  • [6] Computational analysis of antigenic epitopes of avian influenza A (H7N9) viruses
    Mi Liu
    TingRui Song
    Sha Hua
    AiPing Wu
    TaiJiao Jiang
    [J]. Science China Life Sciences, 2015, 58 : 687 - 693
  • [7] Atypical H7N9 avian influenza
    Joob, Beuy
    Wiwanitkit, Viroj
    [J]. CHINESE MEDICAL JOURNAL, 2014, 127 (13) : 2491 - 2491
  • [8] Highly Pathogenic Avian H7N9 Influenza Viruses: Recent Challenges
    Ma, Mai-Juan
    Yang, Yang
    Fang, Li-Qun
    [J]. TRENDS IN MICROBIOLOGY, 2019, 27 (02) : 93 - 95
  • [9] Risk assessment of the newly emerged H7N9 avian influenza viruses
    Chang, Pengxiang
    Sadeyen, Jean-Remy
    Bhat, Sushant
    Daines, Rebecca
    Hussain, Altaf
    Yilmaz, Huseyin
    Iqbal, Munir
    [J]. EMERGING MICROBES & INFECTIONS, 2023, 12 (01)
  • [10] Computational analysis of antigenic epitopes of avian influenza A (H7N9) viruses
    Liu Mi
    Song TingRui
    Hua Sha
    Wu AiPing
    Jiang TaiJiao
    [J]. SCIENCE CHINA-LIFE SCIENCES, 2015, 58 (07) : 687 - 693
12345