Tackling malaria transmission at a single cell level in an endemic setting in sub-Saharan Africa

被引：4

作者：

Dara, Antoine ^{[1
]}

Dogga, Sunil Kumar ^{[2
]}

Rop, Jesse ^{[2
]}

Ouologuem, Dinkorma ^{[1
]}

Tandina, Fatalmoudou ^{[1
]}

Talman, Arthur M. ^{[3
]}

Djimde, Abdoulaye ^{[1
]}

Lawniczak, Mara K. N. ^{[2
]}

机构：

[1] Univ Sci Tech & Technol Bamako USTTB, Fac Pharm, Malaria Res & Training Ctr MRTC, GPO Box 1805, Bamako, Mali

[2] Wellcome Sanger Inst, Hinxton CB10 1SA, England

[3] Univ Montpellier, MIVEGEC, IRD, CNRS, Montpellier, France

来源：

NATURE COMMUNICATIONS | 2022年 / 13卷 / 01期

关键词：

PLASMODIUM-FALCIPARUM; GENETIC DIVERSITY;

D O I：

10.1038/s41467-022-30268-w

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Studying malaria transmission biology using scRNA-sequencing provides information on within-host strain diversity and transcriptional states. Here, we comment on our collaborative efforts at establishing single-cell capacities in sub-Saharan Africa and the challenges encountered in Mali's endemic setting.

引用

页数：3

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