Generalization of the effects of phonological training for anomia using structural equation modelling: A multiple single-case study

被引：21

作者：

Vitali, P. ^{[1
,2
,3
,4
]}

Tettamanti, M. ^{[3
,4
]}

Abutalebi, J. ^{[3
,4
]}

Ansaldo, A. -I. ^{[1
,2
]}

Perani, D. ^{[3
,4
]}

Cappa, S. F. ^{[3
,4
]}

Joanette, Y. ^{[1
,2
]}

机构：

[1] Inst Univ Geriatrie Montreal, Ctr Rech, Montreal, PQ H3W 1W5, Canada

[2] Univ Montreal, Fac Med, Montreal, PQ H3C 3J7, Canada

[3] Hosp San Raffaele, Inst Sci, I-20132 Milan, Italy

[4] Univ Vita Salute, Milan, Italy

来源：

NEUROCASE | 2010年 / 16卷 / 02期

基金：

加拿大健康研究院;

关键词：

fMRI; Aphasia recovery; Effective connectivity; Phonological training; Generalization; NAMING DISORDERS; CHRONIC APHASIA; NONFLUENT APHASIA; BRAIN PLASTICITY; FRONTAL-CORTEX; FUNCTIONAL MRI; LANGUAGE; THERAPY; RECOVERY; FMRI;

D O I：

10.1080/13554790903329117

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Structural Equation Modelling analysis of three longitudinal er-fMRI sessions was used to test the impact of phonological training and of the generalization process on the pattern of brain connectivity during overt picture naming in two chronic anomic patients. Phonological training yielded a positive effect on the trained material. Six months after the training, a generalization of the positive impact on the untrained items was also observed. Connectivity analysis showed that training and generalization effects shared paralleled cortical patterns of functional integration. These findings may represent the neurophysiological correlate of the training-induced cognitive strategies for the compensation of anomia.

引用

页码：93 / 105

页数：13

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