Synthesis of N-Aryl Amides by Ligand-Free Copper-Catalyzed ipso-Amidation of Arylboronic Acids with Nitriles

被引：10

作者：

Qiao, Yan ^{[1
]}

Li, Gaoqiang ^{[1
]}

Liu, Sha ^{[1
]}

Yangkai, Yujie ^{[1
]}

Tu, Jingxuan ^{[1
]}

Xu, Feng ^{[1
]}

机构：

[1] Shaanxi Normal Univ, Key Lab Macromol Sci Shaanxi Prov, Sch Chem & Chem Engn, Xian 710062, Shaanxi, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2017年 / 49卷 / 08期

基金：

中国国家自然科学基金;

关键词：

amides; nitriles; amination; copper catalysis; arylboronic acids; tandem reactions; COUPLING REACTION; BOND FORMATION; ARYLATION; AMINES; BENZOYLATION; REDUCTION; AMINATION; HALIDES;

D O I：

10.1055/s-0036-1588373

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile copper-catalyzed ipso-amidation of arylboronic acids with nitriles has been developed. The method provides a highly efficient and economical synthesis of N-aryl amides with a broad substrate scope.

引用

页码：1834 / 1838

页数：5

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