Monte Carlo dose computation for IMRT optimization

被引：48
|
作者：
Laub, W [1 ]
Alber, M [1 ]
Birkner, M [1 ]
Nüsslin, F [1 ]
机构：
[1] Univ Tubingen, Radiol Uniklin, Abt Med Phys, D-72076 Tubingen, Germany
来源：
PHYSICS IN MEDICINE AND BIOLOGY | 2000年 / 45卷 / 07期
关键词：
D O I：
10.1088/0031-9155/45/7/303
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A method which combines the accuracy of Monte Carlo dose calculation with a finite size pencil-beam based intensity modulation optimization is presented. The pencil-beam algorithm is employed to compute the fluence element updates for a converging sequence of Monte Carlo dose distributions. The combination is shown to improve results over the pencil-beam based optimization in a lung tumour case and a head and neck case. Inhomogeneity effects like a broader penumbra and dose build-up regions can be compensated for by intensity modulation.
引用
收藏
页码：1741 / 1754
页数：14
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