Chiral Primary-Secondary Diamines Catalyzed Michael-Aldol-Dehydration Reaction between Benzoylacetates and α,β-Unsaturated Ketones: Highly Enantioselective Synthesis of Functionalized Chiral Cyclohexenones

被引：44

作者：

Yang, Ying-Quan ^{[1
]}

Chai, Zhuo ^{[2
]}

Wang, Hai-Feng ^{[2
]}

Chen, Xing-Kuan ^{[2
]}

Cui, Hai-Feng ^{[2
]}

Zheng, Chang-Wu ^{[2
]}

Xiao, Hua ^{[1
]}

Li, Peng ^{[2
]}

Zhao, Gang ^{[1
,2
]}

机构：

[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2009年 / 15卷 / 48期

基金：

中国国家自然科学基金;

关键词：

aldol reaction; asymmetric catalysis; enones; Michael reaction; organocatalysis; OPTICALLY-ACTIVE 5-(TERT-BUTYLDIMETHYLSILOXY)-2-CYCLOHEXENONE; CYCLOHEXANE RINGS; BUILDING-BLOCKS; ORGANOCATALYSIS; CONDENSATION; ALDEHYDES; ENONES;

D O I：

10.1002/chem.200901541

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

"Chemical Equation Presented" A highly enantioselective organocatalytic tandem Michael-aldol-dehydration reaction that provides an expedited access to highly functionalized chiral cyclohexenone derivatives (such as that depicted) by using a simple diamine catalyst is described. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：13295 / 13298

页数：4

共 34 条

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