Clinical Features of Invasive Fungal Infections: Aspergillosis, Candidiasis and Mucormycosis

Invasive fungal infection (IFI) is an important cause of morbidity and mortality especially in immunosupressed patients. They can range widely in severity; while mucocutaneous infections are more frequent, fungal infections can be life threatening in some patients. Candida and Aspergillus species are the most common causes of IFIs. Candida spp. have become important causes of sepsis in hospitals, with incidence constantly growing over the last 20 years. Invasive aspergillosis is the second most common IFI, with increasing incidence over the last two decades along with the advances in the treatment of hematological malignancies. Mucormycosis is the second most common invasive mould infection. Agents like Mucor spp. can cause devastating infections.