A versatile approach to 3-alkyl and 2,3-dialkylpyrroles

被引：3
|
作者：
Burley, I
Bilic, B
Hewson, AT
Newton, JRA
机构：
[1] Sheffield Hallam Univ, Div Chem, Sheffield S1 1WB, S Yorkshire, England
[2] Sheffield Hallam Univ, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 46期
基金：
英国工程与自然科学研究理事会;
关键词：
pyrrolines; aromatisation; pyrroles; intramolecular Wittig;
D O I：
10.1016/S0040-4039(00)01591-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A route is described towards N-benzoyl-3-alkyl and N-benzoyl-2,3-dialkyl pyrroles from alpha -amido-ketones via an intramolecular Wittig reaction to afford 4-phenylthio-3-pyrrolines which are then oxidised to the corresponding sulphones and aromatised by treatment with potassium t-butoxide. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8969 / 8972
页数：4
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