A facile one-pot synthesis of thiazo[2′,3′:2,1] imidazo[4,5-b]pyrane;: Thiazo[2′,3′:2,1]imidazo [4,5,b]pyridine;: Imidazo[2,1-b]thiazole and 2-(2-amino-4-methylthiazolo-5-yl)-1-bromo-1,2-ethanedione-1-arylhydrazines

被引：0
|
作者：
Sayed, SM [1 ]
Selim, MA
Raslan, MA
Khalil, MA
机构：
[1] Univ S Valley, Fac Sci, Dept Chem, Aswan 81528, Egypt
[2] Univ S Valley, Fac Sci, Dept Chem, Qena, Egypt
来源：
HETEROATOM CHEMISTRY | 2000年 / 11卷 / 05期
关键词：
D O I：
10.1002/1098-1071(2000)11:5<362::AID-HC7>3.0.CO;2-N
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Thiazole 1, when reacted with chloroacetyl chloride, afforded N-(5-acetyl-4-methylthiazol-2-yl) chloroacetamide 2. It has been found that compound 2 reacted with alpha-cyanocinnamonitrile derivatives 6a-c to afford reaction products 8a-c. Also, compound 2 coupled smoothly with benzenediazonium chloride afforded the phenylhydrazone 14. Coupling of the sulfonium bromide 17 with diazotized aromatic amines or N-nitrosoacetanilides afforded the arylhydrazones 20a,b. Treatment of 16 with 2-cyanoethanethioamide afforded [4-(2-amino-4-methylfhiazol-5-yl) thiazol-2-yl] acetonitrile 22. (C) 2000 John Wiley & Sons, Inc.
引用
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页码：362 / 369
页数：8
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