Iodine-131 whole-body scintigraphy differentiated thyroid carcinoma

Version 4 of the procedural guideline for Iodine-131 whole-body scintigraphy (WBS) in differentiated thyroid carcinoma is an update of the version 3, which was published by the "Deutsche Gesellschaft fur Nuklearmedizin" (DGN) and the "Deutsche Gesellschaft fur Medizinische Physik" (DGMP) in 2007. This procedural guideline advises on how to best perform 1-131 whole body scintigraphy after I-131 therapy or after application of a diagnostic I-131 activity. The updated relevant medical indications for I-131 whole body scintigraphy are given in this procedural guideline. Novel insights on the relationship bet-, ween activity and image quality were incorporated in the updated recommendations. A representative expert group has discussed and reached consensus on the procedural guideline; the development of this procedural guideline therefore fulfils the criteria for level S1 (first step) within the classification of the German Workgroup of Scientific Medical Societies ("Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften"; AWMF). Additionally, indications for WBS, timing and activity for WBS were discussed by the working group "Thyroid" of the DGN on November 30th 2012, April 19th, 2013 and on April 23rd, 2015.