PI3K Inhibitor Increased Radiosensitizing Effect of PARP Inhibitor in BRCA-Proficient Triple Negative Breast Cancer Cells

被引：0
|
作者：
Kim, I. A. [1 ,2 ]
Jang, N. Y. [3 ]
Kim, D. H. [2 ]
Cho, B. J. [4 ]
Choi, E. J. [2 ]
机构：
[1] Seoul Natl Univ, Seoul, South Korea
[2] Seoul Natl Univ, Bundang Hosp, Med Sci Res Inst, Songnam, South Korea
[3] Seoul Natl Univ, Grad Sch Med, Seoul, South Korea
[4] Seoul Natl Univ, Bundang Hosp, Med Sci Res Inst, Songnam, South Korea
来源：
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2015年 / 93卷 / 03期
关键词：
D O I：
10.1016/j.ijrobp.2015.07.1912
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3337
引用
收藏
页码：E533 / E534
页数：2
相关论文
共 50 条
  • [41] HS-173, a novel PI3K inhibitor enhances radiosensitivity of breast cancer cells
    Lee, H.
    Park, J. H.
    Jung, K. H.
    Lim, J. H.
    Hong, S-S
    INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 2022, 20 (02): : 347 - 352
  • [42] PI3K p110α inhibition sensitizes cervical cancer cells with aberrant PI3K signaling activation to PARP inhibitor BMN673
    Cao, Penglong
    Wang, Yingxin
    Lv, Yunyi
    Jiang, Nan
    Zhong, Lin
    Ma, Xiaolu
    Xiao, Xiaoguang
    Ding, Dapeng
    Gu, Juebin
    Lin, Lin
    Li, Shijun
    ONCOLOGY REPORTS, 2019, 42 (05) : 2097 - 2107
  • [43] Antitumor effect and mechanisms research of the PARP inhibition combination with platinum salts and PI3K inhibition on human triple negative breast cancer cell
    Zhang, Jin
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [44] PI3Kγδ inhibitor combined radiation enhances the antitumor immune effect of PD-1 blockade in syngenic triple negative breast cancer models.
    Kim, In Ah
    Han, Min Guk
    Jang, Bum Sup
    Kang, Mi Hyun
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [45] A nano-cocktail of the PARP inhibitor talazoparib and CDK inhibitor dinaciclib for the treatment of triple negative breast cancer
    Paige Baldwin
    Shicheng Yang
    Adrienne Orriols
    Sherrie Wang
    Needa Brown
    Srinivas Sridhar
    Cancer Nanotechnology, 2024, 15
  • [46] Rad51 inhibition sensitizes breast cancer stem cells to PARP inhibitor in triple-negative breast cancer
    Wang, Dong
    Du, Ruikai
    Liu, Suling
    CHINESE JOURNAL OF CANCER, 2017, 36
  • [47] A nano-cocktail of the PARP inhibitor talazoparib and CDK inhibitor dinaciclib for the treatment of triple negative breast cancer
    Baldwin, Paige
    Yang, Shicheng
    Orriols, Adrienne
    Wang, Sherrie
    Brown, Needa
    Sridhar, Srinivas
    CANCER NANOTECHNOLOGY, 2024, 15 (01)
  • [48] Rad51 inhibition sensitizes breast cancer stem cells to PARP inhibitor in triple-negative breast cancer
    Dong Wang
    Ruikai Du
    Suling Liu
    癌症, 2017, 36 (06) : 245 - 246
  • [49] Statin induces inhibition of triple negative breast cancer (TNBC) cells via PI3K pathway
    Park, Yeon Hee
    Jung, Hae Hyun
    Ahn, Jin Seok
    Im, Young-Hyuck
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 439 (02) : 275 - 279
  • [50] PI3K Inhibition Sensitizes Patient-derived Tumor Graft Models of Triple Negative Breast Cancer to PARP Inhibition
    Ibrahim, Y.
    Garcia Garcia, C.
    He, L.
    Serra, V.
    Anton, P.
    Guzman, M.
    Cozar, P.
    Ellison, L.
    Scaltriti, M.
    Baslega, J.
    EUROPEAN JOURNAL OF CANCER, 2012, 48 : S251 - S252
12345