Magnetic resonance imaging as a tool for monitoring stem cell migration

被引：12
|
作者：
Magnitsky, S.
Walton, R. M.
Wolfe, J. H.
Poptani, H.
机构：
[1] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
[2] Univ Penn, Ctr Comparat Med Genet, Philadelphia, PA 19104 USA
[3] Childrens Hosp Philadelphia, Stokes Res Inst, Philadelphia, PA 19104 USA
来源：
NEURODEGENERATIVE DISEASES | 2007年 / 4卷 / 04期
关键词：
neural stem cells; cell tracking; magnetic resonance imaging; iron oxide particles;
D O I：
10.1159/000101888
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Noninvasive monitoring of stem cells is an important step in developing stem-cell-based therapies. Among several imaging techniques available, magnetic resonance imaging (MRI) provides an effective way to detect implanted stem cells in live animals. In this mini-review, we discuss the available MRI contrast agents and different cell-labeling strategies used for detection of stem cell migration in the brain. The potential effects of MRI contrast agents on stem cell viability and differentiation are also discussed. Copyright (c) 2007 S. Karger AG, Basel.
引用
收藏
页码：314 / 321
页数：8
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